| Type | Description |
|---|---|
| Definition | Inositol-requiring enzyme-1 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 16:01:00 | IRE1 promotes neurodegeneration through autophagy-dependent neuron death in the Drosophila model of Parkinson's disease. | 31641108 |
| 2020-09-05 13:58:00 | Genotoxic stress triggers the activation of IRE1alpha-dependent RNA decay to modulate the DNA damage response. | 32409639 |
| 2018-06-09 11:16:00 | XBP1-independent IRE1 RNase activity, while challenging the importance of RNase-independent effector mechanisms of Drosophila IRE1 function. | 28775151 |
| 2017-11-25 15:41:00 | the IRE1/XBP1 endoplasmic reticulum (ER) stress signaling module mediates metabolic adaptation upon dietary restriction in flies. | 27783936 |
| 2016-12-17 12:06:00 | The role of Ire1 in compound eye photoreceptors endoplasmic reticulum differentiation. | 26787744 |
| Type | IDs |
|---|---|
| Synonymous | CG4583, Dmel\CG4583, ERN1, IRE-like, IRE1, Ire, Ire-1, dIRE1, dire-1, ire-1, ire1 |
| Gene |
UniProtKB-ID:
A8JR46_DROME
UniprotKB:
A8JR46
UniParc:
UPI00015D9AE0
EMBL:
AE014297
EnsemblGenome:
FBgn0261984
KO:
dme:Dmel_CG4583
|
| Nucleutide sequences |
EMBL-CDS:
ABW08704.1
Gene_ORFName:
Dmel_CG4583,
CG4583
EnsemblGenome_TRS:
FBtr0113248
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0112160
RefSeq:
NP_001097839.1
|
| Others |
UniRef100:
UniRef100_A8JR46
UniRef90:
UniRef90_A8JR46
UniRef50:
UniRef50_A8JR46
UniGene:
Dm.24079
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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