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4234 METTL1

4234

METTL1

methyltransferase like 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition methyltransferase like 1

研究结论

Date Results Publications
2021-01-23 12:59:00 METTL1 limits differentiation and functioning of EPCs derived from human-induced pluripotent stem cells through a MAPK/ERK pathway. 32430183
2020-06-27 11:25:00 METTL1 promotes cell proliferation and migration in HCC. METTL1 exerts oncogenic activities via suppression of PTEN signaling. 31463732
2020-05-30 11:32:00 Overexpression of METTL1 inhibited CC progression by inhibiting HMGA2 through upregulating let-7e miRNA 32135185
2020-01-18 11:13:00 METTL1 acts as a methyltransferase for a subset of internal N(7)-methylguanosine sites in mRNA. 31031084
2020-01-18 11:13:00 The results identify METTL1-dependent N7-methylation of guanosine as a new RNA modification pathway that regulates miRNA structure, biogenesis, and cell migration. 31031083

名称对应

Type IDs
Synonymous C12orf1, TRM8, TRMT8, YDL201w
Gene
UniProtKB-ID: TRMB_HUMAN
UniprotKB: Q9UBP6
UniParc: UPI0000072720, UPI000013CF90
EMBL: AC025165, Y18643, Y18642, AK314851, AK223202, BC000550, X96698
Ensembl: ENSG00000037897
KO: hsa:4234
Nucleutide sequences
EMBL-CDS: CAA77239.1, BAD96922.1, BAG37368.1, CAA77238.1, CAA65470.1, AAH00550.1
Ensembl_TRS: ENST00000324871, ENST00000257848
Protein sequencees
Ensembl_PRO: ENSP00000257848, ENSP00000314441
RefSeq: XP_005268930.1, NP_005362.3, NP_075422.3, XP_016874794.2
Others
UniRef100: UniRef100_Q9UBP6
UniRef90: UniRef90_Q9UBP6
UniRef50: UniRef50_Q9UBP6
UniGene: Hs.42957
CCDS: CCDS8956.1, CCDS8955.3

全选

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