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42273 dnk

42273

dnk

deoxyribonucleoside kinase

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition deoxyribonucleoside kinase

研究结论

Date Results Publications
2016-05-14 11:41:00 We showed that sensitivity of the osteosarcoma cell line to the nucleoside analogs and the efficiency of bystander cell killing were independent of the subcellular localization of Dm-dNK. 26134602
2016-04-02 11:47:00 Report synergistic antitumor effect of adenovirus armed with Drosophila melanogaster deoxyribonucleoside kinase and nucleoside analogs for human breast carcinoma. 26203222
2015-02-14 12:59:00 Data indicate that long term Dm-dNK ( nucleoside kinase from Drosophila melanogaster) expression rescued thymidine kinase 2 (Tk2)-deficient mice without lethal side effects. 25296759
2013-05-04 11:37:00 Transgene expression of Drosophila melanogaster nucleoside kinase reverses mitochondrial thymidine kinase 2 deficiency 23288848
2011-11-05 12:51:00 Multisubstrate deoxyribonucleoside kinase could be used in a novel therapeutic strategy for treating breast cancer and improving anti-tumor efficacy, as well as for optimizing approaches for suicide gene therapy. 21674733

名称对应

Type IDs
Synonymous CG5452, DM-dNK, DNK, Dm-dNK, DmdNK, Dmel\CG5452, dNK
Gene
UniProtKB-ID: DNK_DROME, Q540Z9_DROME
UniprotKB: Q9XZT6, Q540Z9
UniParc: UPI00000011B7
EMBL: AF185268, AE014297, AY102689, AF045610, Y18048
EnsemblGenome: FBgn0022338
KO: dme:Dmel_CG5452
Nucleutide sequences
EMBL-CDS: CAB41881.1, AAD47355.2, AAF55615.1, AAD56545.1, AGB96102.1, AAM27518.1
Gene_ORFName: CG5452, CG5452, Dmel_CG5452
EnsemblGenome_TRS: FBtr0321263, FBtr0083707, FBtr0321263, FBtr0083707
Protein sequencees
EnsemblGenome_PRO: FBpp0083121, FBpp0302815, FBpp0302815, FBpp0083121
RefSeq: NP_524399.1, NP_001262722.1
Others
UniRef100: UniRef100_Q9XZT6
UniRef90: UniRef90_Q9XZT6
UniRef50: UniRef50_Q9XZT6
UniGene: Dm.1248

全选

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