| Type | Description |
|---|---|
| Definition | Endophilin A |
| Date | Results | Publications |
|---|---|---|
| 2017-07-29 12:39:00 | EndophilinA-induced macroautophagy is activated when the kinase LRRK2 phosphorylates the EndophilinA-BAR domain and is blocked in animals where EndophilinA cannot be phosphorylated. Functionally, deregulation of the EndophilinA phosphorylation state accelerates activity-induced neurodegeneration. | 27720484 |
| 2011-01-15 11:16:00 | analysis of endophilin-A N-BAR domain mutations performed in living flies | 20209138 |
| 2010-01-21 00:00:00 | At fly photoreceptor synapses Endophilin is localized to synaptic vesicles at sites of endocytosis that are glial invaginations called capitate projections; when the photoreceptor synapses lack Endophilin they are impaired in neurotransmitter release | 14627659 |
| 2010-01-21 00:00:00 | In the absence of synaptojanin or endophilin, vesicles undergo full fusion and re-formation. | 16269341 |
| 2010-01-21 00:00:00 | endophilin A is essential for synaptic vesicle endocytosis, being required from the onset of budding until fission. | 11927550 |
| Type | IDs |
|---|---|
| Synonymous | CG14296, D-endo, D-endoA, Dendo-A, Dmel\CG14296, Endo, endo, endoA |
| Gene |
UniProtKB-ID:
SH3G3_DROME,
B5RIU6_DROME
UniprotKB:
Q8T390,
B5RIU6
UniParc:
UPI000007DD7B
EMBL:
AJ437141,
BT003300,
BT044220,
AF426170,
AE014297,
BT099781
EnsemblGenome:
FBgn0038659
KO:
dme:Dmel_CG14296
|
| Nucleutide sequences |
EMBL-CDS:
AAF55606.2,
AAO25060.1,
AAL24818.1,
CAD24682.1,
ACH92285.1,
AAF55605.2,
ACV88440.1,
AGB96097.1
Gene_ORFName:
CG14296,
Dmel_CG14296,
CG14296
EnsemblGenome_TRS:
FBtr0083699,
FBtr0083698,
FBtr0334522,
FBtr0083698,
FBtr0334522,
FBtr0083699
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0083112,
FBpp0083113,
FBpp0306589,
FBpp0083113,
FBpp0083112,
FBpp0306589
RefSeq:
NP_732383.1,
NP_001262717.1,
NP_620122.2
|
| Others |
UniRef100:
UniRef100_Q8T390
UniRef90:
UniRef90_Q8T390
UniRef50:
UniRef50_Q8T390
UniGene:
Dm.3503
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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