| Type | Description |
|---|---|
| Definition | meprin A subunit beta |
| Date | Results | Publications |
|---|---|---|
| 2020-07-04 11:37:00 | The authors found that increased meprin beta G32R activity at the cell surface reduces cell proliferation, but increases cell invasion. | 31076514 |
| 2020-06-13 11:34:00 | As meprin beta cleavage of APP has been shown to result in formation of highly aggregation-prone, truncated Abeta2-40/42 peptides, enhanced APP processing by this enzyme could contribute to Alzheimer's disease pathology. | 31604820 |
| 2018-11-03 12:04:00 | Results provide evidence that meprin beta is involved in collagen deposition in vivo in the lung of bleomycin treated mice and it localized in region with immature collagen. This suggests that meprin beta can favor the progression of the fibrotic process enhancing collagen processing and deposition. | 28059112 |
| 2018-08-04 10:37:00 | This secreted cysteine protease potently converts membrane-bound meprin beta into its active form, impairing meprin beta shedding and its function as a mucus-detaching protease | 29166602 |
| 2018-03-10 12:05:00 | For meprin beta a reduction and for BMP-1 an increase in activity was reported under increasing calcium concentrations. | 28365001 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
MEP1B_HUMAN,
J3QKX5_HUMAN
UniprotKB:
Q16820,
J3QKX5
UniParc:
UPI0000201B8B,
UPI000013F994
EMBL:
AY695931,
CH471088,
BC136559,
AC011825,
BC144244,
X81333,
AC015563
Ensembl:
ENSG00000141434
KO:
hsa:4225
|
| Nucleutide sequences |
EMBL-CDS:
AAI36560.1,
CAA57107.1,
AAI44245.1,
AAU05377.1,
EAX01284.1
Gene_ORFName:
hCG_25081
Ensembl_TRS:
ENST00000269202,
ENST00000581447
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000269202,
ENSP00000463280
RefSeq:
XP_011524315.1,
XP_011524316.1,
NP_005916.2,
NP_001295100.1
|
| Others |
UniRef100:
UniRef100_Q16820,
UniRef100_J3QKX5
UniRef90:
UniRef90_Q16820
UniRef50:
UniRef50_Q16820
UniGene:
Hs.194777
CCDS:
CCDS45846.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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