| Type | Description |
|---|---|
| Definition | heartless |
| Date | Results | Publications |
|---|---|---|
| 2017-09-23 13:42:00 | Mactosylceramide, an early product in GSL biosynthesis, prevents inappropriate activation of insulin and fibroblast growth factor receptors in Drosophila glial cells and hypertrophy. | 28019653 |
| 2015-08-22 11:35:00 | Proliferation of epithelial sheath progenitors, the apical cells, was decreased in both htl and ths mutants, while ectopic expression of the Ths ligand led to these cells' over-proliferation suggesting that FGF signaling supports ovarian muscle sheath formation by controlling apical cell number in the developing gonad. | 25958090 |
| 2014-09-13 10:50:00 | Our data identify FGF signaling through Heartless as a key regulator of astrocyte morphological elaboration in vivo. | 25033182 |
| 2014-01-18 10:48:00 | identify two transcriptional regulators that function downstream of Heartless signaling in lymph gland progenitors, the ETS protein, Pointed, and the Friend-of-GATA protein, U-shaped, which are required for this Heartless-induced differentiation response | 23603494 |
| 2010-01-21 00:00:00 | identified a region within the N terminus of Dof protein that is required for FGF-dependent signal transduction and is necessary for efficient interaction of Dof with the FGF receptor Heartless | 14993266 |
| Type | IDs |
|---|---|
| Synonymous | CG7223, CT22273, CT39172, DFGF-R1, DFGF-R2, DFR-1, DFR1, DFR1/DFGF-R2, DPR3, DTRK(FR1), Dfr-1, Dfr1, DmHD-38, Dmel\CG7223, Dtk1, EMS2, FGF-R2, FGFR, FGFR2, FR1, Fr1, HD-38, HTL/FGFR1, Htl, Tk1, dtk1, i100, i150, i79, j372 |
| Gene |
UniProtKB-ID:
FGFR1_DROME
UniprotKB:
Q07407
UniParc:
UPI000012490B
EMBL:
D14976,
AE014297,
D14977,
AY051812,
X74030,
AJ002913,
S55969
EnsemblGenome:
FBgn0010389
KO:
dme:Dmel_CG7223
|
| Nucleutide sequences |
EMBL-CDS:
BAA03617.1,
AAK93236.1,
AAN13755.1,
CAA05748.1,
AAF55490.1,
AAF55489.1,
CAA52189.1,
BAA03616.1,
AAB19903.1
Gene_ORFName:
CG7223
EnsemblGenome_TRS:
FBtr0083548,
FBtr0083550,
FBtr0083549
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0082970,
FBpp0082971,
FBpp0082972
RefSeq:
NP_732287.1,
NP_524394.2,
NP_732286.1
|
| Others |
UniRef100:
UniRef100_Q07407
UniRef90:
UniRef90_Q07407
UniRef50:
UniRef50_Q07407
UniGene:
Dm.7690
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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