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42066 cher

42066

cher

cheerio

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition cheerio

研究结论

Date Results Publications
2018-06-09 10:06:00 The PDZ domain binding motif found in the most C-terminal region of the Sema-1a ICD is necessary for interaction with Vari, but not Cher, indicative of distinct binding modalities. Pbl/Sema-1a-mediated repulsive guidance is potentiated by both vari and cher Genetic analyses further suggest that scaffolding functions of Vari and Cher play an important role in Pbl-mediated Sema-1a reverse signaling. 28894005
2017-11-04 12:50:00 FLN90, an isoform of the Drosophila ortholog Filamin/cheerio that lacks the actin-binding domain, is here shown to govern the growth of postsynaptic membrane folds and the composition of glutamate receptor clusters at the larval neuromuscular junction. 27914199
2017-08-05 10:12:00 Here we show using Drosophila indirect flight muscle that the filamin ortholog Cheerio in conjunction with the giant elastic protein titin plays a crucial role in keeping thin filaments stably anchored at the Z-disc. We identify the filamin domains required for interaction with the titin ortholog Sallimus, and we demonstrate a genetic interaction of filamin with titin and actin. 28732005
2013-11-23 11:54:00 study identifies Cher as a new target of JNK signaling that links cytoskeleton dynamics to tumor progression. 23239028
2012-02-18 10:35:00 Data indicate that during embryonic development, the expression of Filamin and Ten-m partially overlap in ectodermal cells. 21857973

名称对应

Type IDs
Synonymous CG3937, Cher, Dmel\CG3937, FLN, FLN90, Fil, joy, sko
Gene
UniProtKB-ID: FLNA_DROME, B7Z0L2_DROME, A0A0B4JCY6_DROME, A0A0B4KG47_DROME, A0A0B4KGT8_DROME, Q7KSF4_DROME, A0A0B4KGB3_DROME, A4V310_DROME, A0A0B4KHN1_DROME
UniprotKB: Q9VEN1, B7Z0L2, A0A0B4JCY6, A0A0B4KG47, A0A0B4KGT8, Q7KSF4, A0A0B4KGB3, A4V310, A0A0B4KHN1
UniParc: UPI001396659F, UPI0001F7703E, UPI00019149BD, UPI00139665C9, UPI00019149BB, UPI0002ADBE56, UPI0000083C78, UPI00019149BC, UPI00000075B6
EMBL: AF188361, AF174492, BT133034, AE014297, AF188360, AF183182
EnsemblGenome: FBgn0014141
KO: dme:Dmel_CG3937
Nucleutide sequences
EMBL-CDS: AAF04109.1, AAF04108.1, AAF55390.4, AAF25614.1, AAG43432.1, AAN13734.1, ACL83525.1, AEX93120.1, ADV37329.1, AGB96037.2, AGB96038.1, AAS65162.2, AGB96036.1, AAN13735.2, AGB96039.2
Gene_ORFName: CG3937, Dmel_CG3937, CG3937, CG3937, Dmel_CG3937, Dmel_CG3937, CG3937, CG3937, Dmel_CG3937, CG3937, Dmel_CG3937, Dmel_CG3937, CG3937, CG3937, Dmel_CG3937, CG3937, Dmel_CG3937
EnsemblGenome_TRS: FBtr0089471, FBtr0332167, FBtr0089473, FBtr0290013, FBtr0303364, FBtr0337101, FBtr0290014, FBtr0337100, FBtr0089473, FBtr0332167, FBtr0290015, FBtr0337102
Protein sequencees
EnsemblGenome_PRO: FBpp0304476, FBpp0088480, FBpp0088478, FBpp0288452, FBpp0292427, FBpp0308015, FBpp0288453, FBpp0308014, FBpp0304476, FBpp0088480, FBpp0288454, FBpp0308016
RefSeq: NP_001189238.1, NP_001262657.2, NP_001262658.1, NP_732208.2, NP_732207.1, NP_996224.2, NP_001262656.1, NP_524383.3, NP_001138067.1, NP_001262659.2
Others
UniRef100: UniRef100_A0A0B4KGB3, UniRef100_A0A0B4KHN1, UniRef100_B7Z0L2, UniRef100_A0A0B4KGT8, UniRef100_A0A0B4KG47, UniRef100_Q9VEN1
UniRef90: UniRef90_B7Z0L2, UniRef90_Q9VEN1
UniRef50: UniRef50_Q9VEN1, UniRef50_B7Z0L2
UniGene: Dm.6964

全选

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研究热度

热点单位
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