| Type | Description |
|---|---|
| Definition | myocyte enhancer factor 2A |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:24:00 | Histone methyltransferase MLL4 controls myofiber identity and muscle performance through MEF2 interaction. | 32544095 |
| 2020-07-18 12:12:00 | MEF2A silencing promoted cell senescence and down-regulated PI3K/p-AKT/Sirtuin 1 (SIRT1) expression in vascular endothelial cells. MEF2A overexpression delayed cell senescence and up-regulated PI3K/p-AKT/SIRT1. MEF2A directly up-regulated the expression of PIK3CA and PIK3CG through MEF2 binding sites in the promoter region. | 31182679 |
| 2019-09-14 10:08:00 | MEF2A knockdown accelerates human coronary artery endothelial cells senescence, and the underlying molecular mechanism may be involved in down-regulation of the genes related with cell proliferation, development, inflammation and survival, in which PIK3CG may play a key role. | 30885136 |
| 2019-08-17 11:51:00 | MEF2 acetylation is required for development and maintenance of pathological cardiac hypertrophy, blocking MEF2 acetylation can permit recovery from hypertrophy without impairing physiologic adaptation | 28878124 |
| 2018-10-20 12:06:00 | PCGME1 silencing by small interfering RNA significantly induced early cell apoptosis but this effect was reduced by a miR148a inhibitor. In conclusion, the present study demonstrated a positive regulatory association between MEF2 and PCGEM1, and a reciprocal negative regulatory association between PCGEM1 and miR148a that controls cell apoptosis. | 29749452 |
| Type | IDs |
|---|---|
| Synonymous | ADCAD1, RSRFC4, RSRFC9, mef2 |
| Gene |
UniProtKB-ID:
MEF2A_HUMAN,
A0A0S2Z4C8_HUMAN,
A0A0S2Z4N0_HUMAN,
A0A0S2Z417_HUMAN,
A8K720_HUMAN,
A0A0S2Z454_HUMAN,
A0A0S2Z453_HUMAN
UniprotKB:
Q02078,
A0A0S2Z4C8,
A0A0S2Z4N0,
A0A0S2Z417,
A8K720,
A0A0S2Z454,
A0A0S2Z453
UniParc:
UPI00005A8CB1,
UPI0000073025,
UPI000002ADD2,
UPI000002ADD3,
UPI00017A6F64,
UPI000002ADD4,
UPI000012EEB3,
UPI00004568BF,
UPI00015DA85E
EMBL:
KU178185,
AC015660,
Y16312,
U49018,
AB208985,
U44889,
U49012,
U49017,
U49020,
U49016,
KU178181,
KU178184,
BC053871,
KU178182,
AC022692,
AK294207,
BC013437,
U49019,
X68503,
CH471101,
U49013,
KU178183,
AC103967,
U49015,
X63381,
X68505,
AK291835
Ensembl:
ENSG00000068305
KO:
hsa:4205
|
| Nucleutide sequences |
EMBL-CDS:
AAH13437.1,
AAB17195.1,
AAB17196.1,
CAA48517.1,
CAA76175.1,
BAG57518.1,
CAA44979.1,
BAD92222.1,
AAH53871.1,
CAA48516.1,
ALQ33643.1,
ALQ33641.1,
EAX02252.1,
ALQ33642.1,
BAF84524.1,
ALQ33639.1,
EAX02250.1,
EAX02249.1,
ALQ33640.1
Gene_ORFName:
hCG_1993173,
hCG_1993173,
hCG_1993173
Ensembl_TRS:
ENST00000449277,
ENST00000557942,
ENST00000338042,
ENST00000354410,
ENST00000558812,
ENST00000557785
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000453441,
ENSP00000399460,
ENSP00000346389,
ENSP00000454120,
ENSP00000453095,
ENSP00000337202
RefSeq:
NP_001352140.1,
NP_001165365.1,
XP_016877691.1,
NP_001352130.1,
NP_001352138.1,
NP_001306135.1,
NP_001352133.1,
NP_001339547.1,
XP_011519892.1,
XP_011519881.1,
NP_001339544.1,
NP_001352134.1,
NP_001352136.1,
NP_001339545.1,
NP_001352132.1,
NP_001124399.1,
NP_001352135.1,
XP_011519884.1,
NP_001352131.1,
NP_001124398.1,
XP_011519887.1,
XP_011519889.1,
XP_016877685.1,
NP_001352139.1,
XP_011519875.1,
XP_011519880.1,
XP_011519874.1,
XP_016877684.1,
NP_005578.2,
XP_016877690.1,
XP_016877689.1,
XP_016877680.1,
XP_005254973.1,
NP_001339543.1,
NP_001124400.1,
XP_016877686.1,
XP_016877687.1,
NP_001352137.1,
XP_016877688.1,
XP_011519879.1,
NP_001339546.1
|
| Others |
UniRef100:
UniRef100_Q02078-6,
UniRef100_A8K720,
UniRef100_Q02078,
UniRef100_Q02078-5,
UniRef100_Q02078-2,
UniRef100_Q02078-8
UniRef90:
UniRef90_Q02078,
UniRef90_Q02078-2,
UniRef90_Q02078-5,
UniRef90_Q02078-7
UniRef50:
UniRef50_Q02078-2,
UniRef50_Q02078-7,
UniRef50_Q02078,
UniRef50_Q02078-5
UniGene:
Hs.268675
CCDS:
CCDS81920.1,
CCDS45363.1,
CCDS53978.1,
CCDS45362.1,
CCDS58401.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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