| Type | Description |
|---|---|
| Definition | cathelicidin antimicrobial peptide |
| Date | Results | Publications |
|---|---|---|
| 2019-01-12 10:52:00 | In the absence of an infectious stimulus, in ovo administration of a CATH-2 analog alters the microbiota composition but does not affect the chicks' immune system posthatch. | 29870564 |
| 2018-06-23 10:31:00 | These current observations suggest that CATH1, -2 and -3 in the vagina are upregulated by IL1B, and CATH3 in the uterus is also upregulated by IL6. | 28728035 |
| 2017-11-11 11:49:00 | L-CATH-2, D-CATH-2 and LL-37 can modulate the immune response of primary chicken immune cells by increasing mannose receptor expression, antigen presentation, endocytosis and neutralizing LPS-induced cytokine production and as a result augment activation of the adaptive immune system. | 28715682 |
| 2016-06-11 10:46:00 | CAMP and CATHB1 were significantly up-regulated in bone marrow cells, whereas the expression of CATH3 did not differ significantly between chicken bone marrow cells and chicken embryonic fibroblasts. | 26908883 |
| 2016-01-30 10:16:00 | Here, recombinant fowlicidin-2 was successfully produced by E. coli recombinant expression system.The recombinant peptide exhibited high antibacterial activity against the Gram-positive and Gram-negative bacteria, and even drug-resistant strains. | 25641948 |
| Type | IDs |
|---|---|
| Synonymous | CATH-2, CATH2, CATHL2, CMAP27 |
| Gene |
UniProtKB-ID:
CTHL2_CHICK,
C4PFJ8_CHICK
UniprotKB:
Q2IAL7,
C4PFJ8
UniParc:
UPI0000692160
EMBL:
DQ092352,
DQ092350,
FJ938358,
AY817057
Ensembl:
ENSGALG00000019696
KO:
gga:420407
|
| Nucleutide sequences |
EMBL-CDS:
AAZ42400.1,
AAZ65842.1,
AAX20012.1,
ACR22843.1
Ensembl_TRS:
ENSGALT00000031294
|
| Protein sequencees |
Ensembl_PRO:
ENSGALP00000030658
RefSeq:
NP_001020001.2
|
| Others |
UniRef100:
UniRef100_Q2IAL7
UniRef90:
UniRef90_Q2IAL7
UniRef50:
UniRef50_Q2IAL7
UniGene:
Gga.9531
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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