TSKU - tsukushi, small leucine rich proteoglycan-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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419088 TSKU

基因描述

Type	Description
Definition	tsukushi, small leucine rich proteoglycan

研究结论

Date	Results	Publications
2011-11-05 11:11:00	targeted inactivation of the TSK gene in mice causes expansion of the ciliary body and up-regulation of Wnt2b and Fzd4 expression in the developing peripheral eye	21856951
2010-06-14 11:37:00	The anterior expression is not fixed in the period of limb development, but the expression domains of Mkp3, Sef and TSK change considerably from the distal domain to the anterior domain	20100248
2010-01-21 00:00:00	TSK isoforms play a crucial role in chick axis formation by locally modulating VG1 and BMP activities during gastrulation.	16943268

名称对应

Type	IDs
Synonymous	C-TSK, C-TSKB, EIIH, LRRC54
Gene	UniProtKB-ID: TSK_CHICK UniprotKB: Q65Z91 UniParc: UPI00003FE378, UPI0000D89856 EMBL: AB100033, AB195969 Ensembl: ENSGALG00000000761 KO: gga:419088
Nucleutide sequences	EMBL-CDS: BAD99276.1, BAD44777.1 Ensembl_TRS: ENSGALT00000001106
Protein sequencees	Ensembl_PRO: ENSGALP00000001104 RefSeq: NP_001005346.1
Others	UniRef100: UniRef100_Q65Z91 UniRef90: UniRef90_Q65Z91 UniRef50: UniRef50_Q65Z91 UniGene: Gga.43824

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
21856951	Tsukushi functions as a Wnt signaling inhibitor by competing with Wnt2b for binding to transmembrane protein Frizzled4. Proc. Natl. Acad. Sci. U.S.A. Kunimasa Ohta , Ayako Ito , Sei Kuriyama , Giuseppe Lupo , Mitsuko Kosaka , Shin-ichi Ohnuma , Shinichi Nakagawa , Hideaki Tanaka	2011-09-06	Calb1, Calb2, Fzd4, Smad1, Smad2, Smad3, Msx1, Otx1, Pax6, S100b, Stx1a, Wnt2b, Tsku, FZD4, WNT2B, TSKU
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
20100248	Anterior shift in gene expression precedes anteriormost digit formation in amniote limbs. Dev. Growth Differ. Asaka Uejima , Takanori Amano , Naoki Nomura , Miyuki Noro , Taiji Yasue , Toshihiko Shiroishi , Kunimasa Ohta , Hitoshi Yokoyama , Koji Tamura	2010-02-01	IL17RD, TSKU
16943268	Tsukushi cooperates with VG1 to induce primitive streak and Hensen's node formation in the chick embryo. Development Kunimasa Ohta , Sei Kuriyama , Tatsuya Okafuji , Ryu Gejima , Shin-ichi Ohnuma , Hideaki Tanaka	2006-10-01	TSKU
16319115	Tsukushi controls ectodermal patterning and neural crest specification in Xenopus by direct regulation of BMP4 and X-delta-1 activity. Development Sei Kuriyama , Giuseppe Lupo , Kunimasa Ohta , Shin-Ichi Ohnuma , William A Harris , Hideaki Tanaka	2006-01-01	-
15363410	Tsukushi functions as an organizer inducer by inhibition of BMP activity in cooperation with chordin. Dev. Cell Kunimasa Ohta , Giuseppe Lupo , Sei Kuriyama , Roger Keynes , Christine E Holt , William A Harris , Hideaki Tanaka , Shin-Ichi Ohnuma	2004-09-01	-

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