例如:"NBL1", "4681", "drought"
收藏
419070 GDPD5

419070

GDPD5

glycerophosphodiester phosphodiesterase domain containing 5

protein-coding

Gallus gallus

基因描述

Type Description
Definition glycerophosphodiester phosphodiesterase domain containing 5

研究结论

Date Results Publications
2016-03-05 11:04:00 Prdx4 dimers generated by hydrogen peroxide metabolism oxidize two cysteine residues within the GDE2 enzymatic domain, which blocks GDE2 trafficking to the plasma membrane and prevents GDE2 neurogeneic function. 25943695
2013-01-26 11:17:00 This study identifies a previously unrecognized mechanism to initiate neurogenesis that involves GDE2-mediated surface cleavage of GPI-anchored targets to inhibit Dll1-Notch signaling. 23329048
2010-05-03 11:07:00 Study shows that Galphai2 function is mediated in part by its interaction with GDE2, a known regulator of motor neuron differentiation, and that disruption of the GDE2/Galphai2 complex in vivo causes motor neuron deficits analogous to Galphai2 ablation. 20197066
2010-01-21 00:00:00 a retinoid-inducible gene, GDE2 (glycerophosphodiester phosphodiesterase 2), encoding a six-transmembrane protein that is necessary and sufficient to drive spinal motor neuron differentiation in vivo was identified 16195461
2010-01-21 00:00:00 Study identified the antioxidant enzyme Prdx1 as an interactor of GDE2 and uncover a developmental role for Prdx1 in regulating neuronal differentiation in the spinal cord. 19766572

名称对应

Type IDs
Synonymous GDE2
Gene
UniProtKB-ID: A0A1D5PB53_CHICK, A0A1D5NU41_CHICK
UniprotKB: A0A1D5PB53, A0A1D5NU41
UniParc: UPI000739B22D, UPI0002C86D07
EMBL: AADN05001070
Ensembl: ENSGALG00000034967
KO: gga:419070
Nucleutide sequences
Ensembl_TRS: ENSGALT00000083727, ENSGALT00000062021, ENSGALT00000051976
Protein sequencees
Ensembl_PRO: ENSGALP00000064348, ENSGALP00000049973, ENSGALP00000043850
RefSeq: XP_025006519.1, XP_015136463.1, XP_015136462.1, NP_001292079.1, XP_015136465.1, XP_015136464.1
Others
UniRef100: UniRef100_A0A1D5PB53, UniRef100_A0A1D5NU41
UniRef90: UniRef90_Q3KTM2, UniRef90_A0A674H2L5
UniRef50: UniRef50_Q640M6
UniGene: Gga.13301

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员