| Type | Description |
|---|---|
| Definition | glycerophosphodiester phosphodiesterase domain containing 5 |
| Date | Results | Publications |
|---|---|---|
| 2016-03-05 11:04:00 | Prdx4 dimers generated by hydrogen peroxide metabolism oxidize two cysteine residues within the GDE2 enzymatic domain, which blocks GDE2 trafficking to the plasma membrane and prevents GDE2 neurogeneic function. | 25943695 |
| 2013-01-26 11:17:00 | This study identifies a previously unrecognized mechanism to initiate neurogenesis that involves GDE2-mediated surface cleavage of GPI-anchored targets to inhibit Dll1-Notch signaling. | 23329048 |
| 2010-05-03 11:07:00 | Study shows that Galphai2 function is mediated in part by its interaction with GDE2, a known regulator of motor neuron differentiation, and that disruption of the GDE2/Galphai2 complex in vivo causes motor neuron deficits analogous to Galphai2 ablation. | 20197066 |
| 2010-01-21 00:00:00 | a retinoid-inducible gene, GDE2 (glycerophosphodiester phosphodiesterase 2), encoding a six-transmembrane protein that is necessary and sufficient to drive spinal motor neuron differentiation in vivo was identified | 16195461 |
| 2010-01-21 00:00:00 | Study identified the antioxidant enzyme Prdx1 as an interactor of GDE2 and uncover a developmental role for Prdx1 in regulating neuronal differentiation in the spinal cord. | 19766572 |
| Type | IDs |
|---|---|
| Synonymous | GDE2 |
| Gene |
UniProtKB-ID:
A0A1D5PB53_CHICK,
A0A1D5NU41_CHICK
UniprotKB:
A0A1D5PB53,
A0A1D5NU41
UniParc:
UPI000739B22D,
UPI0002C86D07
EMBL:
AADN05001070
Ensembl:
ENSGALG00000034967
KO:
gga:419070
|
| Nucleutide sequences |
Ensembl_TRS:
ENSGALT00000083727,
ENSGALT00000062021,
ENSGALT00000051976
|
| Protein sequencees |
Ensembl_PRO:
ENSGALP00000064348,
ENSGALP00000049973,
ENSGALP00000043850
RefSeq:
XP_025006519.1,
XP_015136463.1,
XP_015136462.1,
NP_001292079.1,
XP_015136465.1,
XP_015136464.1
|
| Others |
UniRef100:
UniRef100_A0A1D5PB53,
UniRef100_A0A1D5NU41
UniRef90:
UniRef90_Q3KTM2,
UniRef90_A0A674H2L5
UniRef50:
UniRef50_Q640M6
UniGene:
Gga.13301
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员