| Type | Description |
|---|---|
| Definition | specifically Rac1-associated protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-04 12:06:00 | The study examined aspects of sensory and cognitive function in flies harboring a mutation in Cyfip, the homologue of one of the genes within the deletion. | 31202490 |
| 2017-12-09 11:53:00 | These results illustrate a new model to explain the cellular roles of FMRP and CYFIP1 and the molecular significance of their interaction. | 28183735 |
| 2013-06-29 11:28:00 | We propose that Cyfip regulates synapse development and endocytosis by inhibiting actin assembly. | 23593037 |
| 2011-11-26 10:35:00 | Mutations in WAVE/SCAR and in complex subunits but not in WASP, another major regulator of Actin nucleation, phenocopy CYFIP defects. Thus, the pathway orchestrates specific tissue remodeling processes | 21884694 |
| 2010-01-21 00:00:00 | CYFIP specifically expressed in the nervous system; mutations affect axons and synapses, much like mutations in dFMR1 and Rho GTPase dRac1; CYFIP acts as a dRac1 effector that antagonizes FMR1 function | 12818175 |
| Type | IDs |
|---|---|
| Synonymous | CG4931, CYFIP, CYFIP1/2, DSra-1, Dmel\CG4931, PIR121, PIR121/Sra-1, Sra, Sra-1/CYFIP, Sra1, Sra1/PIR121, cyfip, dSra, sra-1, sra1 |
| Gene |
UniProtKB-ID:
CYFIP_DROME
UniprotKB:
Q9VF87
UniParc:
UPI000007536A
EMBL:
AY122203,
AY029211,
AE014297,
BT011115,
AY017343
EnsemblGenome:
FBgn0038320
KO:
dme:Dmel_CG4931
|
| Nucleutide sequences |
EMBL-CDS:
AAK31584.1,
AAM52715.1,
AAG61254.1,
AAF55173.1,
AAR82782.1
Gene_ORFName:
CG4931
EnsemblGenome_TRS:
FBtr0083085
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0082541
RefSeq:
NP_650447.1
|
| Others |
UniRef100:
UniRef100_Q9VF87
UniRef90:
UniRef90_Q9VF87
UniRef50:
UniRef50_Q96F07
UniGene:
Dm.3506
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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