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418257 AICDA

418257

AICDA

activation induced cytidine deaminase

protein-coding

Gallus gallus

基因描述

Type Description
Definition activation induced cytidine deaminase

研究结论

Date Results Publications
2018-08-07 16:05:00 The results, therefore, identify residues in AID involved in its in vivo targeting and suggest they might act through interaction with CTNNBL1, giving possible insight into the linkage between AID recruitment and target-gene transcription. 18722174
2018-08-07 16:04:00 Cis-acting DNA boundary elements restrict AID activity to the IgL locus and guard the genome in the vicinity of the IgL gene from deleterious mutations. 18023479
2017-09-23 10:46:00 findings demonstrate that Bach2 promotes immunoglobulin gene conversion (GCV by increasing the expression of activation-induced cytidine deaminase (AID); regulation of AID is independent of Blimp-1 and BACH2-deficient cells have altered expression of several genes regulating AID expression, stability and function 28301039
2017-06-24 10:53:00 These results suggest that SRSF1-3 (a splicing isoform of SRSF1)promotes nuclear localization of AID probably by forming a nuclear protein complex, which might stabilize nuclear AID and induce immunoglobulin variable region diversification in an AID C-terminus-dependent manner. 28235482
2016-04-16 10:37:00 Studies indicate that gene conversion mediated by activation-induced cytidine deaminase (AID) has been found to contribute to generation of the primary antibody repertoire. 26537386

名称对应

Type IDs
Synonymous AID
Gene
UniProtKB-ID: E1BVI0_CHICK
UniprotKB: E1BVI0
UniParc: UPI00004473A7
EMBL: AADN05000817
Ensembl: ENSGALG00000014280
KO: gga:418257
Nucleutide sequences
Ensembl_TRS: ENSGALT00000023094
Protein sequencees
Ensembl_PRO: ENSGALP00000023051
RefSeq: NP_001230151.1
Others
UniRef100: UniRef100_E1BVI0
UniRef90: UniRef90_E1BVI0
UniRef50: UniRef50_Q9GZX7
UniGene: Gga.41079

全选

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研究热度

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