| Type | Description |
|---|---|
| Definition | HTRA2-related serine protease |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:26:00 | Neuroprotective function of Omi to alpha-synuclein-induced neurotoxicity. | 31837423 |
| 2013-06-15 11:01:00 | Mitochondrial serine protease HtrA2/Omi is an important mediator of germ cell death. | 23523076 |
| 2011-10-22 11:14:00 | Data show the presence of apoptosis at the cellular level in both ade2 and Prat mutants, and the upregulated gene HtrA2, which encodes an apoptosis effector and is thus a candidate for initiating apoptosis in response to purine depletion. | 21441212 |
| 2010-01-21 00:00:00 | Drosophila Omi (dOmi), a fly homologue of the serine protease Omi/HtrA2, alleviates th/DIAP1 inhibition of all caspases by proteolytically degrading th/DIAP1 and induces apoptosis both in cultured cells and in the developing fly eye. | 17557079 |
| 2010-01-21 00:00:00 | found that Rhomboid-7, a mitochondrial protease not previously implicated in PD, acts as an upstream component of this pathway, and showed that it is required to cleave the precursor forms of both Pink1 and Omi | 19048081 |
| Type | IDs |
|---|---|
| Synonymous | CG8464, DmHtrA2, Dmel\CG8464, HtrA2/Omi, Omi, Omi/HtrA2, dOmi, domi, htrA2, htrA2/omi, omi |
| Gene |
UniProtKB-ID:
HTRA2_DROME,
A0A0B4KG52_DROME
UniprotKB:
Q9VFJ3,
A0A0B4KG52
UniParc:
UPI0000076E14
EMBL:
AE014297,
AB112473,
AY075206
EnsemblGenome:
FBgn0038233
KO:
dme:Dmel_CG8464
|
| Nucleutide sequences |
EMBL-CDS:
AAL68074.1,
AAF55062.1,
BAE72064.1,
AGB95946.1
Gene_ORFName:
CG8464,
Dmel_CG8464,
CG8464
EnsemblGenome_TRS:
FBtr0330045,
FBtr0082987,
FBtr0330045,
FBtr0082987
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0082446,
FBpp0303078,
FBpp0303078,
FBpp0082446
RefSeq:
NP_650366.1,
NP_001262565.1
|
| Others |
UniRef100:
UniRef100_Q9VFJ3
UniRef90:
UniRef90_Q9VFJ3
UniRef50:
UniRef50_Q9VFJ3
UniGene:
Dm.5609
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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