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41743 PR-Set7

41743

PR-Set7

PR/SET domain containing protein 7

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition PR/SET domain containing protein 7

研究结论

Date Results Publications
2020-03-28 11:20:00 PR-Set7 fine-tunes the transcriptional activation of Wingless signaling in Drosophila 30733189
2019-08-03 12:00:00 PR/SET domain containing protein 7 methyltransferase (PR-Set7) is targeted for degradation by the ubiquitin-proteasome pathway from G1 to early S phase in Drosophila S2 cells. 29373730
2017-06-24 12:02:00 coincident with the ATR-dependent cell cycle arrest, increased DNA damage is specifically limited to late replicating regions of the Drosophila genome, suggesting that PR-Set7-mediated monomethylation of H4K20 is critical for maintaining the genomic integrity of late replicating domains 27131378
2010-01-21 00:00:00 Results support the hypothesis that methylation of H4 lysine 20 by PR/Set7 maintains silent chromatin, in part, by precluding neighboring acetylation on the H4 tail 12086618
2010-01-21 00:00:00 crystal structure reveals the basis of the specificity of the enzyme for histone H4-K20 15933069

名称对应

Type IDs
Synonymous CG3307, Dmel\CG3307, PR-SET7, PR/SET07, PRSET7, Pr-set-7, PrSet7, SET8, Set7, Set8, dPR-Set7, dSET8, dSet8, l(3)neo41, pr-Set7, pr-set7
Gene
UniProtKB-ID: KMT5A_DROME, A0A0B4K680_DROME
UniprotKB: Q9VFK6, A0A0B4K680
UniParc: UPI00001247DE
EMBL: AY102673, AE014297, AY283060
EnsemblGenome: FBgn0011474
KO: dme:Dmel_CG3307
Nucleutide sequences
EMBL-CDS: AAN13605.1, AAN13606.1, AAF55047.2, AAP35083.1, AAM27502.1, AFH06418.1
Gene_ORFName: CG3307, Dmel_CG3307, CG3307
EnsemblGenome_TRS: FBtr0309996, FBtr0082930, FBtr0082929, FBtr0082929, FBtr0082930, FBtr0309996
Protein sequencees
EnsemblGenome_PRO: FBpp0082389, FBpp0301702, FBpp0082388, FBpp0082389, FBpp0082388, FBpp0301702
RefSeq: NP_650354.1, NP_001247100.1, NP_731900.1
Others
UniRef100: UniRef100_Q9VFK6
UniRef90: UniRef90_Q9VFK6
UniRef50: UniRef50_Q9VFK6
UniGene: Dm.36781

全选

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