| Type | Description |
|---|---|
| Definition | minichromosome maintenance complex component 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-25 11:41:00 | MCM2, MCM4, and MCM6 labeling seems to outperform Ki67 as tools to assess cellular proliferation in breast cancer. The onset of sustained Ki67 expression occurs only in late G1 phase, while MCM can label all proliferative cells during the active phases of cell cycle | 31476594 |
| 2020-04-18 11:19:00 | High MCM4 expression is associated with lung adenocarcinoma. | 31545501 |
| 2020-03-14 11:36:00 | MCM4, MCM5, and MCM8 may have roles in lung adenocarcinoma prognosis with roles in regulating the cell cycle, DNA replication and other multiple biological processes and pathways | 31323040 |
| 2019-10-12 12:36:00 | siRNA of MCM4 inhibits proliferation and induces apoptosis of laryngeal squamous cell carcinoma (LSCC) cell line UMSCC 5. MCM4 mRNA is overexpressed in carcinoma tissues and correlates with male gender, smoking history and poor differentiation in Chinese LSCC patients. | 29135113 |
| 2019-01-12 12:10:00 | Data suggest that MCM4 phosphorylation by CDK2 plays role in DNA replication licensing system MCM4/MCM6/MCM7; this phosphorylation interferes with MCM complex function by lowering stability of MCM complex; MCM4 is highly phosphorylated in S phase. (MCM = minichromosome maintenance complex [hexamer of components 4/6/7]; CDK2 = cyclin-dependent kinase-2) | 30184107 |
| Type | IDs |
|---|---|
| Synonymous | CDC21, CDC54, IMD54, NKCD, NKGCD, P1-CDC21, hCdc21 |
| Gene |
UniProtKB-ID:
MCM4_HUMAN,
B3KMX0_HUMAN,
B4DLA6_HUMAN
UniprotKB:
P33991,
B3KMX0,
B4DLA6
UniParc:
UPI00017A7416,
UPI000013D25C,
UPI000015F62F
EMBL:
AY588245,
AK022899,
U90415,
X74794,
AK296913,
U63630,
BC031061
Ensembl:
ENSG00000104738
KO:
hsa:4173
|
| Nucleutide sequences |
EMBL-CDS:
AAH31061.1,
AAS83108.1,
AAC52018.1,
AAB51723.3,
CAA52801.1,
BAG51132.1,
BAG59468.1
Ensembl_TRS:
ENST00000649973,
ENST00000262105
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000496964,
ENSP00000262105
RefSeq:
NP_005905.2,
NP_877423.1
|
| Others |
UniRef100:
UniRef100_B4DLA6,
UniRef100_P33991,
UniRef100_B3KMX0
UniRef90:
UniRef90_B4DLA6,
UniRef90_P33991
UniRef50:
UniRef50_P33991
UniGene:
Hs.460184
CCDS:
CCDS6143.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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