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41709 foxo

41709

foxo

forkhead box, sub-group O

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition forkhead box, sub-group O

研究结论

Date Results Publications
2021-01-02 12:53:00 AKH-FOXO pathway regulates starvation-induced sleep loss through remodeling of the small ventral lateral neuron dorsal projections. 33104699
2020-08-22 15:29:00 A clinal polymorphism in the insulin signaling transcription factor foxo contributes to life-history adaptation in Drosophila. 31111462
2020-06-27 10:09:00 these data suggest that FOXO temporally regulates olfactory projection neurons cell fate specification 30686090
2020-01-18 10:32:00 Flies lacking fat body fs(1)h exhibit short lifespan, increased expression of immune target genes, an inability to metabolize triglyceride, and low basal AKT activity, mostly resulting from systemic defects in insulin signalling. 30910908
2019-12-21 11:25:00 In Drosophila, reduced insulin/IGF signaling extends lifespan by coordinating activation of Aop and Foxo. Aop and Foxo bind the same genomic loci, and individually, they affect similar transcriptional programs in vivo. In combination, Aop can both moderate or synergise with Foxo, dependent on promoter context. Also, Foxo and Aop oppose the gene-regulatory activity of Pnt. 31356597

名称对应

Type IDs
Synonymous 3143, Afx, CG3143, DFOXO, Dfoxo, DmQ95V5, Dmel\CG3143, FKHR, FOXO, FOXO1, FoxO, Foxo, Q95V55, anon-WO0118547.374, cg3143, dFOXO, dFoxO, dFoxo, dfoxO, dfoxo, fd88A, foxO, foxo, dFOXO
Gene
UniProtKB-ID: FOXO_DROME, A0A126GUT4_DROME, A0A0B4KGN1_DROME
UniprotKB: Q95V55, A0A126GUT4, A0A0B4KGN1
UniParc: UPI0000007591, UPI00019149AE, UPI0004F13E1F, UPI0000080FE1, UPI000237F64C, UPI0000082DF2
EMBL: AF426831, AF416728, AY058718, AE014297, AY089542
EnsemblGenome: FBgn0038197
KO: dme:Dmel_CG3143
Nucleutide sequences
EMBL-CDS: AAF55012.2, AAS65148.1, ACL83512.1, AAS65147.1, AAL09043.1, AAL90280.1, AAL28078.1, AAL13947.1, ALI30566.1, AGB95938.1
Gene_ORFName: CG3143, Dmel_CG3143, CG3143, Dmel_CG3143, CG3143
EnsemblGenome_TRS: FBtr0082886, FBtr0082887, FBtr0346723, FBtr0305052, FBtr0337094
Protein sequencees
EnsemblGenome_PRO: FBpp0089344, FBpp0089343, FBpp0312334, FBpp0308010, FBpp0293589
RefSeq: NP_001262557.1, NP_996205.1, NP_996204.1, NP_650330.3, NP_001303426.1
Others
UniRef100: UniRef100_A0A0B4KGN1, UniRef100_Q95V55, UniRef100_A0A126GUT4
UniRef90: UniRef90_Q95V55, UniRef90_A0A126GUT4, UniRef90_A0A0B4KGN1
UniRef50: UniRef50_B3LYS5, UniRef50_Q95V55
UniGene: Dm.3957

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