| Type | Description |
|---|---|
| Definition | forkhead box, sub-group O |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:53:00 | AKH-FOXO pathway regulates starvation-induced sleep loss through remodeling of the small ventral lateral neuron dorsal projections. | 33104699 |
| 2020-08-22 15:29:00 | A clinal polymorphism in the insulin signaling transcription factor foxo contributes to life-history adaptation in Drosophila. | 31111462 |
| 2020-06-27 10:09:00 | these data suggest that FOXO temporally regulates olfactory projection neurons cell fate specification | 30686090 |
| 2020-01-18 10:32:00 | Flies lacking fat body fs(1)h exhibit short lifespan, increased expression of immune target genes, an inability to metabolize triglyceride, and low basal AKT activity, mostly resulting from systemic defects in insulin signalling. | 30910908 |
| 2019-12-21 11:25:00 | In Drosophila, reduced insulin/IGF signaling extends lifespan by coordinating activation of Aop and Foxo. Aop and Foxo bind the same genomic loci, and individually, they affect similar transcriptional programs in vivo. In combination, Aop can both moderate or synergise with Foxo, dependent on promoter context. Also, Foxo and Aop oppose the gene-regulatory activity of Pnt. | 31356597 |
| Type | IDs |
|---|---|
| Synonymous | 3143, Afx, CG3143, DFOXO, Dfoxo, DmQ95V5, Dmel\CG3143, FKHR, FOXO, FOXO1, FoxO, Foxo, Q95V55, anon-WO0118547.374, cg3143, dFOXO, dFoxO, dFoxo, dfoxO, dfoxo, fd88A, foxO, foxo, dFOXO |
| Gene |
UniProtKB-ID:
FOXO_DROME,
A0A126GUT4_DROME,
A0A0B4KGN1_DROME
UniprotKB:
Q95V55,
A0A126GUT4,
A0A0B4KGN1
UniParc:
UPI0000007591,
UPI00019149AE,
UPI0004F13E1F,
UPI0000080FE1,
UPI000237F64C,
UPI0000082DF2
EMBL:
AF426831,
AF416728,
AY058718,
AE014297,
AY089542
EnsemblGenome:
FBgn0038197
KO:
dme:Dmel_CG3143
|
| Nucleutide sequences |
EMBL-CDS:
AAF55012.2,
AAS65148.1,
ACL83512.1,
AAS65147.1,
AAL09043.1,
AAL90280.1,
AAL28078.1,
AAL13947.1,
ALI30566.1,
AGB95938.1
Gene_ORFName:
CG3143,
Dmel_CG3143,
CG3143,
Dmel_CG3143,
CG3143
EnsemblGenome_TRS:
FBtr0082886,
FBtr0082887,
FBtr0346723,
FBtr0305052,
FBtr0337094
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0089344,
FBpp0089343,
FBpp0312334,
FBpp0308010,
FBpp0293589
RefSeq:
NP_001262557.1,
NP_996205.1,
NP_996204.1,
NP_650330.3,
NP_001303426.1
|
| Others |
UniRef100:
UniRef100_A0A0B4KGN1,
UniRef100_Q95V55,
UniRef100_A0A126GUT4
UniRef90:
UniRef90_Q95V55,
UniRef90_A0A126GUT4,
UniRef90_A0A0B4KGN1
UniRef50:
UniRef50_B3LYS5,
UniRef50_Q95V55
UniGene:
Dm.3957
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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