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4161 MC5R

4161

MC5R

melanocortin 5 receptor

protein-coding

Homo sapiens

基因描述

Type Description
Definition melanocortin 5 receptor

研究结论

Date Results Publications
2020-05-09 12:33:00 MCR5 is a modulator of the responses stimulated by glucose in cells, which might possibly be translated into a modulation of the retinal pigment epithelium response to diabetes in vivo. 30739530
2017-10-28 12:58:00 Mutations in residues S4/S5 and S17/E18 retained MC5R at the ER/Golgi complex and did not affect MC5R homodimerization. 28396017
2016-07-30 11:18:00 melanocortin receptors MC2R, MC3R and MC5R are most abundantly expressed in glandular epithelium of the endometrium 26223677
2016-04-23 10:43:00 MC2R and MC1R signals are consecutively required for the regulation of EPO signal transduction in erythroblast differentiation, and MC5R signal transduction is required to induce enucleation. 25860801
2014-02-01 10:33:00 D115 and D119 in TM3, F195 in TM5, and F254 in TM6 may form a binding pocket for NDP-alpha-MSH binding. 23414113

名称对应

Type IDs
Synonymous MC2
Gene
UniProtKB-ID: MC5R_HUMAN
UniprotKB: P33032
UniParc: UPI0000050405
EMBL: EF444993, CH471113, U08353, Z25470, BC069153, AY268429, L27080, BC069545, BC095531
Ensembl: ENSG00000176136
KO: hsa:4161
Nucleutide sequences
EMBL-CDS: AAH95531.1, CAA80962.1, AAH69545.1, AAA59566.1, AAB60376.1, ACA06012.1, AAP23196.1, AAH69153.1, EAX01504.1
Ensembl_TRS: ENST00000324750, ENST00000589410
Protein sequencees
Ensembl_PRO: ENSP00000318077, ENSP00000468086
RefSeq: NP_005904.1
Others
UniRef100: UniRef100_P33032
UniRef90: UniRef90_P33032
UniRef50: UniRef50_P33033
UniGene: Hs.248145
CCDS: CCDS11868.1

全选

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研究热度

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