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41591 Paip2

41591

Paip2

polyA-binding protein interacting protein 2

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition polyA-binding protein interacting protein 2

研究结论

Date Results Publications
2020-06-06 11:48:00 Paip2 is novel player at stage of mRNA capping & Pol II elongation. Nuclear Paip2 is component of ~300-kDa protein complex. Paip2 interacts with mRNA capping factor and factors of RNA polymerase II (Pol II) transcription initiation and early elongation. Paip2 functionally cooperates with Cbp80 subunit of cap-binding complex, with both proteins ensuring proper Pol II C-terminal domain (CTD) Ser5 phosphorylation at promoter 31001806
2019-11-09 11:29:00 Paip2 is one more item in the growing list of translation factors that are recruited to mRNAs co-transcriptionally. 29995569
2010-01-21 00:00:00 Inhibits cell growth primarily by inhibiting protein synthesis. 14729960

名称对应

Type IDs
Synonymous CG12358, Dmel\CG12358, PAIP2, dPaip2, paip2
Gene
UniProtKB-ID: Q9VG13_DROME
UniprotKB: Q9VG13
UniParc: UPI0000077E17
EMBL: AE014297, KX531722, AY061203, AY333418, BT124998
EnsemblGenome: FBgn0038100
KO: dme:Dmel_CG12358
Nucleutide sequences
EMBL-CDS: AAF54880.1, AAL28751.1, AGB95897.1, ANY27532.1, AAP97744.1, ADI46794.1
Gene_ORFName: Dmel_CG12358, CG12358
EnsemblGenome_TRS: FBtr0334509, FBtr0082693
Protein sequencees
EnsemblGenome_PRO: FBpp0306576, FBpp0082161
RefSeq: NP_001262515.1, NP_524334.1
Others
UniRef100: UniRef100_Q9VG13
UniRef90: UniRef90_Q9VG13
UniRef50: UniRef50_Q9VG13
UniGene: Dm.1658

全选

研究热度

研究结论
热点单位
排名 科研单位 文献
1

University of California

3
2

Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.

2
3

University of Cambridge

2
4

Howard Hughes Medical Institute

2
5

Harvard University

2
热点人员
排名 研究人员 文献
1

Susan E Celniker

7
2

Joseph W Carlson

5
3

Gerald M Rubin

5
4

Gary H Karpen

4
5

Roger A Hoskins

4
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