| Type | Description |
|---|---|
| Definition | melanocortin 3 receptor |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 10:59:00 | positive association between rare heterozygous coding partial/complete loss-of-function mutations and obesity in children and adults of European, North African, and Asian ancestries [meta-analysis] | 31090190 |
| 2020-06-13 10:15:00 | in African-American adults homozygosity for the MC3R C17A + G241A haplotype was associated with a metabolically unhealthy phenotype, including increased BMI, fat mass, fat mass percentage, and systemic inflammation | 30937899 |
| 2020-01-25 10:05:00 | MC3R gene rs 3746619 polymorphism was found associated with polycystic ovary syndrome in the Turkish population and may make a contribution to the genetic baseline of the disease. | 30784330 |
| 2019-06-01 10:17:00 | meta-analysis results supported a recessive inheritance model for MC3R gene as a potential cause of childhood obesity; high clinical heterogeneity existed among studies and thus requires more research of larger participation for future integration of data | 29688747 |
| 2019-02-02 12:05:00 | AgRP acted as a biased agonist in MC3R, decreasing cAMP activity of constitutively active mutant (F347A) MC3R but stimulating ERK1/2 activation in both wild type and F347A MC3Rs. | 27208795 |
| Type | IDs |
|---|---|
| Synonymous | BMIQ9, MC3, MC3-R, OB20, OQTL |
| Gene |
UniProtKB-ID:
MC3R_HUMAN
UniprotKB:
P41968
UniParc:
UPI0000E5A34B
EMBL:
AY227893,
AL139824,
BC069105,
BC098351,
BC096702,
L06155,
BC098169,
BC096737,
BC069599
Ensembl:
ENSG00000124089
KO:
hsa:4159
|
| Nucleutide sequences |
EMBL-CDS:
AAH98351.1,
AAH96737.1,
AAH69599.1,
AAH69105.1,
AAH98169.1,
AAH96702.1,
AAC13541.1,
AAO72726.1
Ensembl_TRS:
ENST00000243911
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000243911
RefSeq:
NP_063941.3
|
| Others |
UniRef100:
UniRef100_P41968
UniRef90:
UniRef90_P41968
UniRef50:
UniRef50_P32245
UniGene:
Hs.248018
CCDS:
CCDS13449.2
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| 1 |
College of Veterinary Medicine |
9 |
| 2 |
Uppsala University |
6 |
| 3 |
National University of Singapore |
4 |
| 4 |
Eunice Kennedy Shriver National Institute of Child Health and Human Development |
4 |
| 5 |
University of Michigan Medical Center |
3 |
| 排名 | 研究人员 | 文献 |
|---|---|---|
| 1 |
Ya-Xiong Tao |
10 |
| 2 |
Jack A Yanovski |
6 |
| 3 |
I Gantz |
5 |
| 4 |
T Yamada |
4 |
| 5 |
R Muceniece |
4 |