| Type | Description |
|---|---|
| Definition | Suppressor of fused |
| Date | Results | Publications |
|---|---|---|
| 2016-05-14 11:08:00 | A Comparison of Ci/Gli Activity as Regulated by Sufu in Drosophila and Mammalian Hedgehog Response | 26271100 |
| 2016-04-30 10:09:00 | Sufu can sequester Ci/Gli in the cytoplasm through binding to an N-terminal site while inhibiting Ci/Gli activity in the nucleus depending on a C-terminal Sufu-interacting site. | 25941387 |
| 2014-12-27 11:28:00 | Drosophila Hedgehog signaling promotes downregulation of Su(fu) through its target protein HIB (Hh-induced BTB protein). | 24603360 |
| 2014-11-08 13:45:00 | Suppressor of fused (Sufu) opposes Trn-mediated Ci nuclear import by masking its PY-nuclear localization sequence. | 24413177 |
| 2014-06-14 13:53:00 | The 'closed' form of Sufu is stabilized by Gli binding and inhibited by Hh treatment, whereas the 'open' state of Sufu is promoted by Gli-dissociation and Hh signaling. | 24217340 |
| Type | IDs |
|---|---|
| Synonymous | CG6054, Dmel\CG6054, SU(FU), SUFU, Su(Fu), SuFu, Sufu, d Sufu, dSufu, su(fu), sufu |
| Gene |
UniProtKB-ID:
Q9VG38_DROME
UniprotKB:
Q9VG38
UniParc:
UPI000007B234
EMBL:
AY069285,
AE014297
EnsemblGenome:
FBgn0005355
KO:
dme:Dmel_CG6054
|
| Nucleutide sequences |
EMBL-CDS:
AAF54852.1,
AAL39430.1
Gene_ORFName:
Dmel_CG6054,
CG6054
EnsemblGenome_TRS:
FBtr0082665
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0082134
RefSeq:
NP_536750.2
|
| Others |
UniRef100:
UniRef100_Q9VG38
UniRef90:
UniRef90_Q9VG38
UniRef50:
UniRef50_Q9VG38
UniGene:
Dm.23318
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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