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415577 BLM

415577

BLM

Bloom syndrome RecQ like helicase

protein-coding

Gallus gallus

基因描述

Type Description
Definition Bloom syndrome RecQ like helicase

研究结论

Date Results Publications
2017-10-14 12:55:00 first enzymatic characterization of chicken BLM and its N-terminal domain 28338731
2017-06-03 12:25:00 BLM is assembled from dimer into hexamer, and also, the stable DHBN dimer can be dissociated upon ATP hydrolysis. Thus, the structural and biochemical characterizations of N-terminal domains will provide new insights into how the N-terminal domain affects the structural and functional organization of the full BLM molecule. 28228481
2010-01-21 00:00:00 Disruption of the BLM gene in ATM-null DT40 cells (a B-lymphocyte cell line)does not exacerbate either phenotype. 14985700
2010-01-21 00:00:00 These data indicate that BLM and Top3alpha execute the dissolution of sister chromatids. 16880537
2010-01-21 00:00:00 These data suggest that Fbh1 acts in parallel with Bloom helicase to control recombination-mediated double-strand-break repair at replication blocks and to reduce the frequency of crossover. 17283053

名称对应

Type IDs
Synonymous ORF1
Gene
UniProtKB-ID: BLM_CHICK
UniprotKB: Q9I920
UniParc: UPI0000443767
EMBL: AJ720413, AB040747
KO: gga:415577
Nucleutide sequences
EMBL-CDS: BAA96742.1, CAG32072.1
Protein sequencees
RefSeq: NP_001007088.2
Others
UniRef100: UniRef100_Q9I920
UniRef90: UniRef90_Q9I920
UniRef50: UniRef50_Q9I920
UniGene: Gga.1914

全选

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研究热度

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