| Type | Description |
|---|---|
| Definition | ELL associated factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-20 12:16:00 | Eaf1 and Eaf2 mediate zebrafish dorsal-ventral axis patterning via suppressing Wnt/beta-Catenin activity. | 29910681 |
| 2017-12-23 10:09:00 | study unveiled a previously unrecognized link of Eaf1/2 genes with TGF-beta and P53 in vertebrates and demonstrated a conservation of TGF-beta suppression activity for Eaf1/2 family genes from fish to mammals, which might shed some light on the molecular mechanistic basis of Eaf1 and Eaf2 in tumor suppression. | 28887217 |
| 2013-04-20 12:01:00 | A novel role for Eaf1 and Eaf2 in inhibiting canonical Wnt/beta-catenin signaling, which might form the mechanistic basis for Eaf1 and Eaf2 tumor suppressor activity. | 23364330 |
| 2010-10-04 12:33:00 | Findings provide the first convincing line of evidence that EAF and Wnt4 form an auto-regulatory negative feedback loop in vivo. | 20161747 |
| 2010-01-21 00:00:00 | eaf1 and eaf2/u19 act upstream of noncanonical Wnt signaling to mediate convergence and extension movements | 19380582 |
| Type | IDs |
|---|---|
| Synonymous | wu:fb76c01, wu:fc43g12, zgc:86600 |
| Gene |
UniProtKB-ID:
Q6IQU8_DANRE
UniprotKB:
Q6IQU8
UniParc:
UPI000037811D
EMBL:
CR394542,
BC071305
Ensembl:
ENSDARG00000010432
KO:
dre:415252
|
| Nucleutide sequences |
EMBL-CDS:
AAH71305.1
Ensembl_TRS:
ENSDART00000021060
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000005794
RefSeq:
NP_001002162.1
|
| Others |
UniRef100:
UniRef100_Q6IQU8
UniRef90:
UniRef90_Q6IQU8
UniRef50:
UniRef50_Q6IQU8
UniGene:
Dr.75486
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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