| Type | Description |
|---|---|
| Definition | ELL associated factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-20 12:16:00 | Eaf1 and Eaf2 mediate zebrafish dorsal-ventral axis patterning via suppressing Wnt/beta-Catenin activity. | 29910681 |
| 2017-12-23 10:09:00 | study unveiled a previously unrecognized link of Eaf1/2 genes with TGF-beta and P53 in vertebrates and demonstrated a conservation of TGF-beta suppression activity for Eaf1/2 family genes from fish to mammals, which might shed some light on the molecular mechanistic basis of Eaf1 and Eaf2 in tumor suppression. | 28887217 |
| 2014-05-10 14:07:00 | eaf1 has a role in suppressing foxo3b expression to modulate transcriptional activity of gata1 and spi1 in primitive hematopoiesis | 24445282 |
| 2013-04-20 12:01:00 | A novel role for Eaf1 and Eaf2 in inhibiting canonical Wnt/beta-catenin signaling, which might form the mechanistic basis for Eaf1 and Eaf2 tumor suppressor activity. | 23364330 |
| 2010-10-04 12:33:00 | Findings provide the first convincing line of evidence that EAF and Wnt4 form an auto-regulatory negative feedback loop in vivo. | 20161747 |
| Type | IDs |
|---|---|
| Synonymous | wu:fb52f06, zgc:86818 |
| Gene |
UniProtKB-ID:
Q6IQD2_DANRE
UniprotKB:
Q6IQD2
UniParc:
UPI0000378189
EMBL:
AL845419,
AL929040,
BC153592,
BC071476
Ensembl:
ENSDARG00000070795,
ENSDARG00000113962
KO:
dre:415205
|
| Nucleutide sequences |
EMBL-CDS:
AAH71476.1,
AAI53593.1
Ensembl_TRS:
ENSDART00000188613,
ENSDART00000104252
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000095027,
ENSDARP00000147168
RefSeq:
NP_001002115.1
|
| Others |
UniRef100:
UniRef100_Q6IQD2
UniRef90:
UniRef90_Q6IQD2
UniRef50:
UniRef50_Q6IQD2
UniGene:
Dr.3524
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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