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4152 MBD1

4152

MBD1

methyl-CpG binding domain protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition methyl-CpG binding domain protein 1

研究结论

Date Results Publications
2019-01-12 12:22:00 ZEB1 silenced SIRT3 expression via interaction with MBD1 to promote aerobic glycolysis in pancreatic cancer. 30487699
2018-02-17 10:08:00 MBD1 may be a tumor suppressor gene in advanced colorectal cancer (CRC)and affect the development and metastasis of CRC by regulating 8 tumor suppressor genes through binding with SP1. 28473981
2018-01-06 11:17:00 Our findings imply that reduced stability and enhanced dynamics of MBD1 or MBD6 is the origin of ATP7B dysfunction in Wilson disease patients with the G85V or G591D mutation. 27744583
2017-10-14 11:22:00 MBD1 regulates localization and activity of Tet1 in a CXXC3 domain-dependent manner. 28449087
2017-08-19 12:35:00 the binding of MBD1 to nucleosomes demonstrates sequence preferences depending on the position of the methyl groups on the nucleosome. 28377300

名称对应

Type IDs
Synonymous CXXC3, PCM1, RFT
Gene
UniProtKB-ID: MBD1_HUMAN, B4DUR3_HUMAN, A8K654_HUMAN, B4DI41_HUMAN
UniprotKB: Q9UIS9, B4DUR3, A8K654, B4DI41
UniParc: UPI0001AE65E5, UPI000013D836, UPI000006CEE8, UPI0001F995B6, UPI00017A71BE, UPI0000072C35, UPI00017A7F94, UPI0000151F37, UPI000013D834, UPI00001A3706, UPI000013D835, UPI00015887CC, UPI00015DA887, UPI0001F995B7
EMBL: AK291519, BC033242, AF078831, AJ564845, AF072241, EF488685, AF078830, AF120980, AK295401, AK300759, AF120981, Y10746, AC090246, AF078832, AF078833, AK302004
Ensembl: ENSG00000141644
KO: hsa:4152
Nucleutide sequences
EMBL-CDS: AAD51443.1, CAA71735.1, AAH33242.1, AAD51445.1, ABP02056.1, AAD51444.1, AAC68870.1, AAD50371.1, CAD92308.1, BAG63407.1, AAD51442.1, BAG62425.1, BAF84208.1, BAG58353.1
Ensembl_TRS: ENST00000398493, ENST00000585672, ENST00000398488, ENST00000591535, ENST00000347968, ENST00000591416, ENST00000353909, ENST00000382948, ENST00000269471, ENST00000588937, ENST00000339998, ENST00000457839, ENST00000590208, ENST00000269468, ENST00000585595, ENST00000587605
Protein sequencees
Ensembl_PRO: ENSP00000381506, ENSP00000467017, ENSP00000466092, ENSP00000269471, ENSP00000465923, ENSP00000339546, ENSP00000381502, ENSP00000468430, ENSP00000467763, ENSP00000405268, ENSP00000269468, ENSP00000468042, ENSP00000372407, ENSP00000269469, ENSP00000285102, ENSP00000468785
RefSeq: NP_001310878.1, NP_001375068.1, NP_001375092.1, NP_001375072.1, NP_001375083.1, NP_001375074.1, NP_001375070.1, NP_001375069.1, NP_001375096.1, XP_016881244.1, NP_001310883.1, NP_001375094.1, NP_001191070.1, NP_001375071.1, XP_016881265.1, NP_002375.1, XP_016881243.1, NP_001375080.1, NP_001310876.1, NP_001375079.1, NP_001191069.1, NP_056669.2, NP_001375076.1, NP_001375089.1, NP_001375082.1, NP_001191072.1, NP_056723.2, NP_001310881.1, NP_001375081.1, NP_001310882.1, NP_001375067.1, NP_056670.2, NP_001310871.1, NP_001375075.1, NP_001375086.1, XP_016881257.1, NP_001375087.1, NP_001375090.1, NP_001375084.1, NP_001310879.1, XP_016881259.1, NP_001375095.1, NP_001191066.1, NP_001375091.1, NP_001375078.1, XP_024306951.1, NP_001191080.1, XP_011524304.1, XP_016881246.1, NP_001375073.1, XP_011524309.1, NP_001375093.1, NP_001191071.1, XP_005258328.1, NP_001375088.1, XP_024306948.1, NP_056671.2, NP_001375077.1, NP_001191068.1, NP_001191065.1, NP_001310880.1, NP_001375085.1, NP_001191067.1
Others
UniRef100: UniRef100_B4DUR3, UniRef100_Q9UIS9-9, UniRef100_Q9UIS9, UniRef100_A8K654
UniRef90: UniRef90_Q9UIS9-9, UniRef90_Q9UIS9-10, UniRef90_Q9UIS9
UniRef50: UniRef50_Q9UIS9, UniRef50_Q9UIS9-10, UniRef50_Q9UIS9-9
UniGene: Hs.405610
CCDS: CCDS11944.1, CCDS11941.1, CCDS59320.1, CCDS56073.1, CCDS32832.1, CCDS59318.1, CCDS11942.1, CCDS59319.1, CCDS56071.1, CCDS11943.1, CCDS56072.1

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