| Type | Description |
|---|---|
| Definition | CD74 molecule |
| Date | Results | Publications |
|---|---|---|
| 2020-06-13 10:10:00 | a novel role of CD74 during IBDV infection, showing that chicken CD74 plays a significant role in IBDV binding to target B cells by interacting with the viral VP2 protein. This is the first report demonstrating that CD74 is involved as a novel attachment receptor in the IBDV life cycle in target B cells, thus contributing new insight into host-pathogen interactions. | 31666381 |
| 2015-09-26 13:18:00 | The cross immunogenicity between Ia-associated invariant chains of chicken and Muscovy duck were located in conserved region. | 25854563 |
| 2015-05-30 10:17:00 | Both host and parasite MIF molecules bind to chicken macrophages via CD74 surface receptor. | 25086294 |
| 2015-05-16 10:47:00 | allele-dependent association of MHC class I molecules with its invariant chain with bases on a multi-site determinative spatial structure | 24948007 |
| 2010-01-21 00:00:00 | cathepsin S is necessary for invariant chain proteolysis in T cells; cathepsin S expression and activity, and concordantly cell surface CLIP expression, was reduced in HLA-DR(+) CD4(+) T cells as compared with B cells | 19553543 |
| Type | IDs |
|---|---|
| Synonymous | CD76, II |
| Gene |
UniProtKB-ID:
Q6J613_CHICK,
F1NYL5_CHICK
UniprotKB:
Q6J613,
F1NYL5
UniParc:
UPI0000377006,
UPI00003AAB38
EMBL:
AADN05000072,
AY597054
Ensembl:
ENSGALG00000004594
KO:
gga:414741
|
| Nucleutide sequences |
EMBL-CDS:
AAT36346.1
Ensembl_TRS:
ENSGALT00000088722,
ENSGALT00000040533
|
| Protein sequencees |
Ensembl_PRO:
ENSGALP00000063230,
ENSGALP00000039736
RefSeq:
XP_015149240.1,
NP_001001613.1
|
| Others |
UniRef100:
UniRef100_Q6J613,
UniRef100_F1NYL5
UniRef90:
UniRef90_F1NYL5,
UniRef90_Q6J613
UniRef50:
UniRef50_D6QUQ3,
UniRef50_Q6J613
UniGene:
Gga.4414
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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