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4145 MATK

4145

MATK

megakaryocyte-associated tyrosine kinase

protein-coding

Homo sapiens

基因描述

Type Description
Definition megakaryocyte-associated tyrosine kinase

研究结论

Date Results Publications
2012-01-07 10:20:00 After IGF-I stimulation, CTK is recruited to IGF-IR and its recruitment facilitates CTK's subsequent association with phospho-SHPS-1. 21799000
2010-01-21 00:00:00 CHK is capable of inhibiting the CXCL12-CXCR4 pathway in neuroblastoma. 18292939
2010-01-21 00:00:00 Overexpression of the Csk homologous kinase facilitates phosphorylation of akt/protein kinase b in breast neoplasms 12429987
2010-01-21 00:00:00 CHK Leu223 stabilizes the movement of the alphaC-helix of the protein tyrosine kinase 12782282
2010-01-21 00:00:00 Nuclear multi-lobulation in late S phase, which is dependent on polymerization and depolymerization of microtubules, may be involved in nuclear Chk-induced inhibition of proliferation. 15748901

名称对应

Type IDs
Synonymous CHK, CTK, HHYLTK, HYL, HYLTK, Lsk
Gene
UniProtKB-ID: MATK_HUMAN, F1T0G6_HUMAN
UniprotKB: P42679, F1T0G6
UniParc: UPI000014A55C, UPI0000000C50, UPI000013FB32
EMBL: S75153, AB593100, S75159, X77278, L18974, S75162, S75145, S75158, S75168, AL137754, BC003109, S75156, S75151, S75166, AK055395, AC005777, S75155, S75147, S75164, CH471139, BC000114
Ensembl: ENSG00000007264
KO: hsa:4145
Nucleutide sequences
EMBL-CDS: CAB70906.2, CAA54493.1, AAA16703.1, AAC62843.1, BAG51511.1, AAC60645.1, EAW69285.1, AAH00114.1, AAH03109.1, BAJ84040.1, EAW69286.1
Gene_ORFName: hCG_23522
Ensembl_TRS: ENST00000619596, ENST00000395040, ENST00000395045, ENST00000310132
Protein sequencees
Ensembl_PRO: ENSP00000378485, ENSP00000308734, ENSP00000483213, ENSP00000378481
RefSeq: XP_011526320.1, NP_002369.2, NP_647611.1, NP_647612.1
Others
UniRef100: UniRef100_P42679
UniRef90: UniRef90_P42679
UniRef50: UniRef50_P42679
UniGene: Hs.631845
CCDS: CCDS12113.1, CCDS42468.1, CCDS12114.1

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