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4144 MAT2A

4144

MAT2A

methionine adenosyltransferase 2A

protein-coding

Homo sapiens

基因描述

Type Description
Definition methionine adenosyltransferase 2A

研究结论

Date Results Publications
2021-01-16 16:00:00 Methionine Adenosyltransferase Engineering to Enable Bioorthogonal Platforms for AdoMet-Utilizing Enzymes. 32091873
2020-05-16 10:45:00 the protein-protein interacting surface formed in MATa2:MATbeta complexes is explored to demonstrate that several quinolone-based compounds modulate the activity of MATa2 and its mutants, providing a rational for chemical design/intervention responsive to the level of S-Adenosylmethionine in the cellular environment 30776190
2019-04-27 10:07:00 The simultaneous downregulation of MAT1A and upregulation of MAT2A are necessary and sufficient for hepatocellular carcinoma metastasis in the process of M1-M2 switch. 29749642
2018-07-21 10:53:00 MAT2A expression is upregulated through mRNA stabilization upon SAM depletion. 29262316
2018-06-30 11:32:00 Increased MAT2A expression is associated with recurrence in hepatocellular carcinoma. 29448301

名称对应

Type IDs
Synonymous MATA2, MATII, SAMS2
Gene
UniProtKB-ID: METK2_HUMAN, A0A140VJP5_HUMAN
UniprotKB: P31153, A0A140VJP5
UniParc: UPI0000000C32, UPI00017A76BE
EMBL: AC016753, X68836, AK316411, AK297758, HM005434, CH471053, BC001686, BC001854, DQ083239, AK291126
Ensembl: ENSG00000168906
KO: hsa:4144
Nucleutide sequences
EMBL-CDS: BAH14782.1, AAH01854.1, AAY85355.1, BAF83815.1, CAA48726.1, EAW99513.1, AAY24339.1, BAG60107.1, EAW99511.1, AAH01686.1, AEE61032.1
Ensembl_TRS: ENST00000306434, ENST00000409017
Protein sequencees
Ensembl_PRO: ENSP00000386353, ENSP00000303147
RefSeq: NP_005902.1
Others
UniRef100: UniRef100_P31153
UniRef90: UniRef90_P31153
UniRef50: UniRef50_P31153
UniGene: Hs.516157
CCDS: CCDS1977.1

全选

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