| Type | Description |
|---|---|
| Definition | Histamine-gated chloride channel subunit 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-02-23 10:57:00 | Study results show that both Ort and HisCl1 define two different pathways for circadian entrainment. Whereas Ort contributes through its expression in the interneurons of the optic lobe, HisCl1 mostly contributes through its expression in the Rh6-expressing retinal photoreceptors. The work thus reveals that Rh6-expressing neurons contribute to light-mediated entrainment as both photoreceptors and interneurons. | 30651542 |
| 2014-04-19 12:09:00 | The activity of HisCl1-expressing neurons is acutely and reversibly silenced by exogenous histamine. | 24550306 |
| 2010-03-29 11:35:00 | may play an essential and conserved role in insect neurophysiology | 19716373 |
| 2010-01-21 00:00:00 | the genes encoding for proteins involved in histamine signaling [histidine decarboxylase (hdc), histamine-gated chloride channel subunit 1 (hisCl1), ora transientless (ort)] cause abnormal temperature preferences | 16822982 |
| 2010-01-21 00:00:00 | These results identify HCLB as an important in vivo target for ivermectin in Drosophila melanogaster, and demonstrate the involvement of this protein in the visual pathway. | 18839229 |
| Type | IDs |
|---|---|
| Synonymous | CG14723, CT34515, DMHisClalpha2, Dm-HCLB, DmHisCl1, Dmel\CG14723, HA-CI II, HisCl-alpha2, hclB, hisCl1 |
| Gene |
UniProtKB-ID:
Q95T69_DROME,
Q8WS32_DROME,
Q9VGI0_DROME,
E1JII9_DROME
UniprotKB:
Q95T69,
Q8WS32,
Q9VGI0,
E1JII9
UniParc:
UPI000007C8A5,
UPI0000004964,
UPI0000083E10,
UPI0001C0001E
EMBL:
AF382402,
AF435470,
AY060303,
AF435471,
AE014297,
AY049775,
AF382401
EnsemblGenome:
FBgn0037950
KO:
dme:Dmel_CG14723
|
| Nucleutide sequences |
EMBL-CDS:
AAL74415.1,
AAL25342.1,
AAS65139.1,
AAN13530.2,
AAL12211.1,
AAL74414.1,
AAL66187.1,
AAF54699.2,
AAL66186.1,
ACZ94888.1
Gene_ORFName:
CG14723,
Dmel_CG14723,
CG14723,
Dmel_CG14723,
CG14723,
Dmel_CG14723,
CG14723,
Dmel_CG14723
EnsemblGenome_TRS:
FBtr0082472,
FBtr0082471,
FBtr0082470,
FBtr0301826
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0089167,
FBpp0089166,
FBpp0081946,
FBpp0291040
RefSeq:
NP_001163591.1,
NP_650116.2,
NP_996196.1,
NP_731632.1
|
| Others |
UniRef100:
UniRef100_Q8WS32,
UniRef100_Q95T69,
UniRef100_E1JII9,
UniRef100_Q9VGI0
UniRef90:
UniRef90_Q9VGI0,
UniRef90_Q95T69
UniRef50:
UniRef50_Q95T69,
UniRef50_Q9VGI0
UniGene:
Dm.10006
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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