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4142 MAS1

4142

MAS1

MAS1 proto-oncogene, G protein-coupled receptor

protein-coding

Homo sapiens

基因描述

Type Description
Definition MAS1 proto-oncogene, G protein-coupled receptor

研究结论

Date Results Publications
2021-02-06 13:55:00 ACE2/Ang-(1-7)/Mas1 axis and the vascular system: vasoprotection to COVID-19-associated vascular disease. 33511992
2021-02-02 13:27:00 Oestrogen-mediated upregulation of the Mas receptor contributes to sex differences in acute lung injury and lung vascular barrier regulation. 32764118
2020-05-02 12:31:00 Ang-(1-7) stimulates beige markers and thermogenesis via the Mas receptor. 31843339
2020-04-11 10:56:00 The production of ANG 1-7 was significantly lower in breast cancer cells, whereas the expression of MAS receptor was higher than that in the control breast tissue cells. This finding suggests that substances with MAS receptor agonist activity could be useful in the treatment of breast cancer. 31642813
2019-08-03 10:51:00 We have hypothesized the mechanism that reverses the downregulation of the ACE2-angiotensin 1-7/Mas receptor axis path and the upregulation of angiotensin receptor type 1-mediated signaling. Thus, we posit that ACE2, Ang-(1-7), and the Mas receptor could be novel therapeutic targets for treating benign prostatic hyperplasia . 30055537

名称对应

Type IDs
Synonymous MAS, MGRA
Gene
UniProtKB-ID: MAS_HUMAN, W8W3P4_HUMAN
UniprotKB: P04201, W8W3P4
UniParc: UPI0000050458
EMBL: BC069581, M13150, CH471051, AL035691, BC110454, CR542261, HG426065, BC069142
Ensembl: ENSG00000130368
KO: hsa:4142
Nucleutide sequences
EMBL-CDS: AAA36199.1, AAI10455.1, EAW47610.1, EAW47611.1, CAG47057.1, AAH69581.1, AAH69142.1, CDG86183.1
Ensembl_TRS: ENST00000252660, ENST00000674077
Protein sequencees
Ensembl_PRO: ENSP00000501180, ENSP00000252660
RefSeq: NP_002368.1, NP_001353633.1
Others
UniRef100: UniRef100_P04201
UniRef90: UniRef90_P04201
UniRef50: UniRef50_P12526
UniGene: Hs.99900
CCDS: CCDS5272.1

全选

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研究热度

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