| Type | Description |
|---|---|
| Definition | methionyl-tRNA synthetase |
| Date | Results | Publications |
|---|---|---|
| 2019-12-21 10:40:00 | MRS/CD45 dual IF staining showed good diagnostic performance and may be a good tool complementing conventional cytology test for determining lymph node metastasis of non-small cell lung cancer. | 31637881 |
| 2019-06-01 13:17:00 | The results establish that the pulmonary alveolar proteinosis-related substitutions in MARS impact the tRNAMet-aminoacylation reaction especially at the level of methionine recognition. | 29775242 |
| 2018-12-22 12:01:00 | Compound Arg618Cys and Tyr307Cys variants were identified in an infant with syndromic interstitial lung and liver disease. Arg618Cys associated with Charcot-Marie-Tooth disease was inherited from an unaffected father. | 29655802 |
| 2018-04-07 11:15:00 | MRS is frequently overexpressed in NSCLC. Moreover, MRS is related to mTORC1 activity and its overexpression is associated with poor clinical outcomes, indicating that it has potential as a putative therapeutic target. | 28679377 |
| 2018-01-20 11:17:00 | Genotype-phenotype correlation analysis suggests most of the interstitial lung and liver disease (ILLD), mutations locate in the catalytic domain of MARS. ILLD and Charcot-Marie-Tooth disease, axonal, type 2U might have different disease mechanism. | 28148924 |
| Type | IDs |
|---|---|
| Synonymous | CMT2U, ILFS2, ILLD, METRS, MRS, MTRNS, SPG70 |
| Gene |
UniProtKB-ID:
SYMC_HUMAN
UniprotKB:
P56192
UniParc:
UPI0000136597,
UPI00005A7AF4
EMBL:
BC015011,
BC011849,
AC022506,
Z49216,
AK222767,
X94754,
BC002384,
D84224,
BC006328,
BT007338,
AK122956,
BC011639
Ensembl:
ENSG00000166986
KO:
hsa:4141
|
| Nucleutide sequences |
EMBL-CDS:
BAG53819.1,
AAH06328.1,
BAA95668.1,
BAD96487.1,
AAH02384.1,
CAA64381.1,
CAA89153.1,
AAP36002.1,
AAH15011.1,
AAH11639.1,
AAH11849.1
Ensembl_TRS:
ENST00000537638,
ENST00000262027
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000262027,
ENSP00000446168
RefSeq:
NP_004981.2,
XP_006719461.1
|
| Others |
UniRef100:
UniRef100_P56192
UniRef90:
UniRef90_P56192
UniRef50:
UniRef50_P56192
UniGene:
Hs.632707
CCDS:
CCDS8942.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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