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4140 MARK3

4140

MARK3

microtubule affinity regulating kinase 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition microtubule affinity regulating kinase 3

研究结论

Date Results Publications
2019-12-07 11:41:00 A non-synonymous homozygous variant (NM_001128918.2: c.1708C > G: p.Arg570Gly) in the MARK3 leads to visual impairment and progressive phthisis bulbi. 29771303
2018-06-16 11:39:00 Authors identified a regulatory switch controlled by MARK3 that couples microtubules to the actin cytoskeleton to establish epithelial cell polarity through ARHGEF2. 29089450
2014-12-20 12:04:00 findings indicate that brain PP-1I associates with and is regulated by the associated protein kinases C-TAK1 and PFTK1 25028520
2014-01-04 12:38:00 We have shown that serum ALP levels modified the association of MARK3 with bone mineral density in osetoporosis for Chinese patients. 23894155
2010-09-15 22:06:00 Observational study of gene-disease association. (HuGE Navigator) 20554715

名称对应

Type IDs
Synonymous CTAK1, KP78, PAR1A, Par-1a, VIPB
Gene
UniProtKB-ID: MARK3_HUMAN, Q86U11_HUMAN
UniprotKB: P27448, Q86U11
UniParc: UPI0000EE3491, UPI000002AE4E, UPI000002AE52, UPI000002AE51, UPI000002AE4D, UPI000002AE50, UPI000002AE4F, UPI000000CBFA
EMBL: BX161395, BC024773, AF387637, AL133367, KF456011, AF159295, BX248250, AF170723, CH471061, AF465413, M80359, U64205
Ensembl: ENSG00000075413
KO: hsa:4140
Nucleutide sequences
EMBL-CDS: AAC15093.1, AAK82367.1, AAD48007.1, AAD51631.1, AAL69982.1, EAW81813.1, EAW81817.1, AAH24773.1, EAW81815.1, CAD61882.1, AAA59991.1, CAD62578.1
Ensembl_TRS: ENST00000553942, ENST00000303622, ENST00000440884, ENST00000216288, ENST00000416682, ENST00000429436
Protein sequencees
Ensembl_PRO: ENSP00000408092, ENSP00000402104, ENSP00000216288, ENSP00000411397, ENSP00000303698, ENSP00000450772
RefSeq: NP_001122393.2, XP_016876797.1, XP_005267699.2, XP_024305357.1, XP_016876796.1, XP_024305355.1, XP_016876784.1, XP_016876782.1, XP_016876787.1, XP_016876781.1, XP_016876783.1, XP_024305354.1, XP_016876780.1, XP_024305358.1, XP_024305352.1, XP_011535071.1, XP_024305351.1, XP_016876785.1, NP_001122390.2, NP_001122391.2, XP_005267698.2, XP_024305359.1, XP_016876786.1, XP_005267700.2, NP_002367.5, XP_024305353.1, XP_016876788.1, XP_016876795.1, XP_016876790.1, NP_001122392.2, XP_024305356.1
Others
UniRef100: UniRef100_Q86U11, UniRef100_P27448
UniRef90: UniRef90_H0YIY6, UniRef90_P27448
UniRef50: UniRef50_Q7KZI7-4, UniRef50_H0YIY6
UniGene: Hs.35828
CCDS: CCDS45166.1, CCDS45167.1, CCDS55947.1, CCDS41993.1, CCDS45165.1

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