例如:"NBL1", "4681", "drought"
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4131 MAP1B

4131

MAP1B

microtubule associated protein 1B

protein-coding

Homo sapiens

基因描述

Type Description
Definition microtubule associated protein 1B

研究结论

Date Results Publications
2020-04-04 11:56:00 These neuritic defects result from impaired Nrf2 activity on antioxidant response elements (AREs) localized to a microtubule-associated protein (Map1b) gene enhancer and are rescued by forced expression of Map1b as well as by both Nrf2 overexpression and pharmaceutical activation in Parkinson's disease (PD) neurons 31235589
2020-02-22 12:49:00 Knockdown of microtubule-associated protein 1B light chain (MAP 1B-LC1) represses E-cadherin downregulation, vimentin upregulation and actin filament remodeling, decreases cell migration and invasion during TGF-beta1-induced epithelial to mesenchymal transition (EMT) in A549 cells. Heterogeneous nuclear ribonucleoprotein K (hnRNP K) promotes the EMT of lung cancer cells induced by TGF-beta1 through interacting with MAP... 31492158
2019-11-02 11:27:00 Calpain-10 regulates actin dynamics by proteolysis of microtubule-associated protein 1B 30425305
2019-05-18 12:37:00 MAP1B-LC1 links microtubules and Stx17 in fed cells, and starvation causes the dephosphorylation of MAP1B-LC1 at Thr217, allowing Stx17 to dissociate from MAP1B-LC1 and bind to Atg14L. 29925525
2019-01-19 12:24:00 High MAP1B expression is associated with resistance to mTOR inhibition in glioblastoma. 29136244

名称对应

Type IDs
Synonymous FUTSCH, MAP5, PPP1R102
Gene
UniProtKB-ID: MAP1B_HUMAN, Q86X89_HUMAN, A2BDK6_HUMAN, Q6PJD3_HUMAN
UniprotKB: P46821, Q86X89, A2BDK6, Q6PJD3
UniParc: UPI00001BDA4F, UPI00001603CD, UPI000000DB33, UPI000013E382
EMBL: L06237, CH471084, BC017240, BN001084, BN001085, AC012609, BC046114, AC093218
Ensembl: ENSG00000131711
KO: hsa:4131
Nucleutide sequences
EMBL-CDS: EAW95697.1, AAA18904.1, CAM06633.1, AAH46114.1, EAW95696.1, CAM12311.1, AAH17240.1
Gene_ORFName: hCG_37848
Ensembl_TRS: ENST00000296755
Protein sequencees
Ensembl_PRO: ENSP00000296755
RefSeq: NP_001311184.1, NP_005900.2
Others
UniRef100: UniRef100_Q86X89, UniRef100_Q6PJD3, UniRef100_P46821, UniRef100_A0A024RAM4
UniRef90: UniRef90_Q8CFR9, UniRef90_P46821
UniRef50: UniRef50_P14400, UniRef50_P15205
UniGene: Hs.335079
CCDS: CCDS4012.1

全选

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