| Type | Description |
|---|---|
| Definition | Iron regulatory protein 1B |
| Date | Results | Publications |
|---|---|---|
| 2018-11-03 11:27:00 | Downregulating Irp-1B in neurons of single-housed Abeta42 expressing and control flies rescued both survival and motor performance deficits. Authors provide novel evidence that increased cerebral expression of Irp-1B may underlie worsened behavioral outcome in socially deprived flies and can additionally modulate AD-like phenotypes. | 29251829 |
| 2010-01-21 00:00:00 | muscle-specific overexpression of IRP-1A, but not of IRP-1B, resulted in pre-adult lethality, underscoring the importance of the biochemical difference between the two proteins;only IRP-1A can bind to iron-responsive elements | 16679315 |
| Type | IDs |
|---|---|
| Synonymous | 144037_at, C-Acon, CG6342, Dmel\CG6342, IRF, IRP, IRP-1, IRP-1B, IRP1, cACON, cAcon, dIRP, irp-1B, irp1B |
| Gene |
UniProtKB-ID:
Q9VGZ3_DROME
UniprotKB:
Q9VGZ3
UniParc:
UPI0000081C73
EMBL:
AE014297
EnsemblGenome:
FBgn0024957
KO:
dme:Dmel_CG6342
|
| Nucleutide sequences |
EMBL-CDS:
AAF54529.1
Gene_ORFName:
Dmel_CG6342,
CG6342
EnsemblGenome_TRS:
FBtr0082259
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0081736
RefSeq:
NP_524303.2
|
| Others |
UniRef100:
UniRef100_Q9VGZ3
UniRef90:
UniRef90_Q9VGZ3
UniRef50:
UniRef50_Q9VGZ3
UniGene:
Dm.1137
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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