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41265 jumu

41265

jumu

jumeau

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition jumeau

研究结论

Date Results Publications
2020-05-09 11:52:00 Loss of Jumeau (Jumu) function triggers apoptosis via a JNK-dependent pathway in wing development. jumu mutants show reduced wing size, a loss of the anterior cross vein (ACV) phenotype, and increased apoptosis. The JNK signaling markers puckered (puc) and p-JNK are increased in the wing discs of jumu mutants. Apoptosis induced by the loss of jumu is rescued by knocking down JNK. 30796611
2019-06-08 12:54:00 Study reports that Drosophila protein Jumu binds N6-methyladenine (6mA)-marked DNA and acts as a maternal factor to regulate the maternal-to-zygotic transition and finds that zelda encoding the pioneer factor Zelda is marked by 6mA. Genetic assays suggest that Jumu controls the proper zygotic genome activation in early embryos, at least in part, by regulating zelda expression. 31101825
2019-05-18 11:33:00 Jumu is required for circulating hemocyte differentiation and phagocytosis in Drosophila 30518379
2017-07-01 11:35:00 The results suggest a Jumu-mediated crosstalk between hematopoiesis and the fat body, especially during the Toll-dependent formation of melanotic nodules. 27507244
2017-05-06 10:38:00 Jumeau (Jumu), a member of the forkhead (Fkh) transcription factor family, controls hemocyte differentiation of lymph gland through multiple regulatory mechanisms. 28350299

名称对应

Type IDs
Synonymous 5295, CG4029, Dmel\CG4029, Dmjumu, Dom, Dwhn, E(var)631, Jumeau, Jumu, Scim31, Whn, jumeaux, jumu/Dom, l(3)06142, l(3)06439
Gene
UniProtKB-ID: Q9XTP7_DROME
UniprotKB: Q9XTP7
UniParc: UPI000007AF96
EMBL: AY061327, AJ243916, AB028890, AF264033, AJ243814, AE014297
EnsemblGenome: FBgn0015396
KO: dme:Dmel_CG4029
Nucleutide sequences
EMBL-CDS: AAL28875.1, CAB51073.1, BAA94598.1, AAF54525.1, CAB51032.1, AAF91395.1
Gene_ORFName: CG4029, Dmel_CG4029
EnsemblGenome_TRS: FBtr0082237
Protein sequencees
EnsemblGenome_PRO: FBpp0081715
RefSeq: NP_524302.1
Others
UniRef100: UniRef100_Q9XTP7
UniRef90: UniRef90_Q9XTP7
UniRef50: UniRef50_Q9XTP7
UniGene: Dm.3109

全选

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