| Type | Description |
|---|---|
| Definition | mannosidase alpha class 1A member 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:28:00 | Markers of malignant prostate cancer cells: Golgi localization of alpha-mannosidase 1A at GM130-GRASP65 site and appearance of high mannose N-glycans on cell surface. | 32331836 |
| 2020-06-20 12:12:00 | These results show an oncogenic role of the Golgi mannosidase MAN1A1 in ovarian cancer, where MAN1A1 expression levels significantly affects recurrence-free and overall survival . Mannosidase-mediated N-glycosylation has a strong impact on tumour cell aggregation and affects the prognostic impact of the adhesion molecule ALCAM. | 31659304 |
| 2018-02-10 10:58:00 | In situ proximity ligation assays of Golgi localization of alpha-mannosidase IA at giantin versus GM130-GRASP65 site, and absence or presence of N-glycans terminated with alpha3-mannose on trans-Golgi glycosyltransferases may be useful for distinguishing indolent from aggressive prostate cancer cells | 28782625 |
| 2015-04-18 13:19:00 | We observed significant lower values of GAL, FUC and tendency to decrease of alpha-mannosidase and GLU concentration in nasal polyps | 23911047 |
| 2011-09-17 10:47:00 | Complex N-glycans generated by enzymes such as a-mannosidase I inhibit the activation of naive T cells. | 21577142 |
| Type | IDs |
|---|---|
| Synonymous | HUMM3, HUMM9, MAN9 |
| Gene |
UniProtKB-ID:
MA1A1_HUMAN
UniprotKB:
P33908
UniParc:
UPI0000237CA2,
UPI000013D632
EMBL:
AL138886,
X74837,
AL022722,
CH471051,
AL078600,
BC065827
Ensembl:
ENSG00000111885
KO:
hsa:4121
|
| Nucleutide sequences |
EMBL-CDS:
EAW48185.1,
AAH65827.1,
CAA52831.1
Ensembl_TRS:
ENST00000368468
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000357453
RefSeq:
NP_005898.2,
XP_005267043.1,
XP_011534135.1,
XP_011534136.1
|
| Others |
UniRef100:
UniRef100_P33908
UniRef90:
UniRef90_P33908
UniRef50:
UniRef50_P33908
UniGene:
Hs.102788,
Hs.742378
CCDS:
CCDS5122.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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