Type | Description |
---|---|
Definition | steroid sulfatase |
Date | Results | Publications |
---|---|---|
2020-09-12 16:06:00 | X-linked ichthyosis: Clinical and molecular findings in 35 Italian patients. | 29672931 |
2020-05-09 11:18:00 | Inhibition of steroid sulfatase by the specific inhibitor STX064 recovered steroid sulfatase -induced oxygen consumption rate repression and lactic acid over-production. Steroid sulfatase expression induced by inflammatory cytokines may exacerbate pulmonary fibrosis, as HIF1alpha expression is highly increased. | 31195119 |
2020-03-21 11:52:00 | Liver-specific STS expression exhibited markedly increased sensitivity to CEE-induced estrogenic activity in the uterus resulting from increased levels of liver-derived and circulating estrogens. | 31217279 |
2020-03-07 12:43:00 | This study is useful for understanding the genetic basis of X-linked ichthyosis (XLI) in the patients studied, for extending the known mutational spectrum of STS, diagnosis of female carriers and for further application of mutation screening in the genetic counseling of this family. | 32005174 |
2019-06-15 12:21:00 | Increased intratumoural metabolism of oestrogens through STS is associated with significantly lower incidence of relapse and/or distant metastasis and correspondingly improved prognosis. The enrichment of STS in the HER2 overexpressing subtype is intriguing, especially given the possible role of HER-2 over-expression in endocrine resistance. | 29563635 |
Type | IDs |
---|---|
Synonymous | ARSC, ARSC1, ASC, ES, SSDD, XLI |
Gene |
UniProtKB-ID:
STS_HUMAN,
A0A590UJL0_HUMAN,
A6PYA4_HUMAN,
Q0W975_HUMAN
UniprotKB:
P08842,
A0A590UJL0,
A6PYA4,
Q0W975
UniParc:
UPI0000136153,
UPI0001582B34,
UPI0000DBDC41,
UPI000387D148
EMBL:
M23945,
AC108685,
AC120338,
AM072429,
KF458961,
AK314034,
AC112651,
AM282551,
M16505,
BC075030,
AM282552,
M23556,
FM209047,
AC074034,
KF458959,
AC073583,
J04964,
AC005704,
AM282553,
AM072428,
AM282554
Ensembl:
ENSG00000101846
KO:
hsa:412
|
Nucleutide sequences |
EMBL-CDS:
BAG36744.1,
AAA60599.1,
AAA60596.1,
AAA60598.1,
AAA60597.1,
AAH75030.1,
CAK54340.1,
CAK54341.1,
CAK54339.1,
CAJ21479.1,
CAR64266.1,
CAJ21480.1,
CAK54338.1
Ensembl_TRS:
ENST00000674499,
ENST00000666110,
ENST00000217961,
ENST00000674429
|
Protein sequencees |
Ensembl_PRO:
ENSP00000501360,
ENSP00000499472,
ENSP00000501534,
ENSP00000217961
RefSeq:
NP_000342.3,
NP_001307681.2,
NP_001307683.1,
NP_001307679.1,
NP_001307680.1,
NP_001307682.1
|
Others |
UniRef100:
UniRef100_A0A590UJL0,
UniRef100_A6PYA4,
UniRef100_H2PUV2,
UniRef100_P08842
UniRef90:
UniRef90_P08842
UniRef50:
UniRef50_P08842
UniGene:
Hs.522578,
Hs.700558,
Hs.700559,
Hs.740067
|
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Refseq |
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