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41181 hyd

41181

hyd

hyperplastic discs

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition hyperplastic discs

研究结论

Date Results Publications
2020-10-24 14:03:00 UBR5 Is Coamplified with MYC in Breast Tumors and Encodes an Ubiquitin Ligase That Limits MYC-Dependent Apoptosis. 32029551
2020-08-01 14:16:00 Hyd mediated Lys63 (K63)-linked polyubiquitination of the NF-kappaB cofactor Akirin was required for efficient binding of Akirin to the NF-kappaB transcription factor Relish. 32339205
2017-09-30 12:03:00 Wnt-dependent inactivation of the Groucho/TLE co-repressor by the HECT E3 ubiquitin ligase Hyd/UBR5 is a key prerequisite that enables Armadillo/beta-catenin to activate transcription. 28689657
2016-05-21 10:25:00 Drosophila-based findings highlight an apical role for Hyd and Sgg in initiating Hedgehog signalling, which could also be evolutionarily conserved in mammals 26334301
2015-06-27 13:23:00 hyperplastic discs (hyd), an E3 ubiquitin ligase, can differentially regulate the transcriptional outputs of Hh signaling. We show that loss of Hyd activity caused upregulation of some, but not all of Hh target genes. 24854243

名称对应

Type IDs
Synonymous CG9484, Dmel\CG9484, HYD, Hyd, NP_524296.2, UBE 3A, UBR5, c43, l(3)85Ea, l(3)C43, l(3)C43-3, l(3)SG33, l(3)c43, l[[3]]c43
Gene
UniProtKB-ID: HYD_DROME, A0A0B4LGZ6_DROME, A0A0H4Y1G5_DROME
UniprotKB: P51592, A0A0B4LGZ6, A0A0H4Y1G5
UniParc: UPI0000076398, UPI0002B8CD85
EMBL: AE014297, BT150484, L14644
EnsemblGenome: FBgn0002431
KO: dme:Dmel_CG9484
Nucleutide sequences
EMBL-CDS: AAB88625.1, AAF54431.2, AHN57261.1, AKR06212.1
Gene_ORFName: CG9484, CG9484, Dmel_CG9484
EnsemblGenome_TRS: FBtr0082090, FBtr0339599, FBtr0082090
Protein sequencees
EnsemblGenome_PRO: FBpp0081568, FBpp0308671, FBpp0081568
RefSeq: NP_001287262.1, NP_524296.2
Others
UniRef100: UniRef100_P51592, UniRef100_A0A0B4LGZ6
UniRef90: UniRef90_P51592
UniRef50: UniRef50_P51592
UniGene: Dm.7365

全选

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