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41104 VhaM8.9

41104

VhaM8.9

Vacuolar H[+] ATPase M8.9 accessory subunit

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Vacuolar H[+] ATPase M8.9 accessory subunit

研究结论

Date Results Publications
2019-04-27 11:35:00 Results suggest that full-length ATP6AP2 contributes to the assembly of the V-ATPase proton pore and that impairment of this function affects ER homeostasis and PCP signaling. 29995586
2017-12-23 12:28:00 the missense mutations in ATP6AP2 lead to impaired V-ATPase assembly and subsequent defects in glycosylation and autophagy. 29127204
2016-08-27 10:25:00 ATP6AP2 disruption leads to cognitive impairment and neurodegeneration, mimicking aspects of the neuropathology associated with ATP6AP2 mutations in humans. 26376863
2013-03-30 10:49:00 Two roles for VhaPRR, one for planar cell polarity and another in endosomal trafficking. This dual function establishes VhaPRR as a key factor in epithelial morphogenesis. 23292348
2010-11-27 11:00:00 The Drosophila protein CG8444 is a prorenin receptor (named herein dPRR), and has an evolutionarily conserved role at the receptor level for activation of canonical and noncanonical Wnt/Fz signaling pathways. 20579883

名称对应

Type IDs
Synonymous ATP6AP2, CG8444, Dmel\CG8444, VhaM8-9, VhaPRR, dPRR, vhaM8.9
Gene
UniProtKB-ID: RENR_DROME
UniprotKB: Q9VHG4
UniParc: UPI000007EFC4
EMBL: AY051790, AE014297
EnsemblGenome: FBgn0037671
KO: dme:Dmel_CG8444
Nucleutide sequences
EMBL-CDS: AAF54350.1, AAK93214.1
Gene_ORFName: CG8444
EnsemblGenome_TRS: FBtr0081978
Protein sequencees
EnsemblGenome_PRO: FBpp0081458
RefSeq: NP_649876.1
Others
UniRef100: UniRef100_Q9VHG4
UniRef90: UniRef90_Q9VHG4
UniRef50: UniRef50_Q9VHG4
UniGene: Dm.4477

全选

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研究热度

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