| Type | Description |
|---|---|
| Definition | neuralized |
| Date | Results | Publications |
|---|---|---|
| 2019-01-19 12:14:00 | Study find that in Drosophila neur is directly regulated in proneural clusters by both proneural transcriptional activators and Enhancer of split basic helix-loop-helix repressors (bHLH-Rs), via two separate cis-regulatory modules within the neur locus. | 30028887 |
| 2018-09-29 10:49:00 | Data show that Neuralized (Neur) regulates collective apical constriction and furrow formation, and the Bearded (Brd) proteins antagonize maternal Neur and lower medial-apical contractility in the ectoderm. | 29150614 |
| 2018-06-23 10:47:00 | The authors found that Dl requires ubi for its full function, but can also signal in two ubi-independent modes, one dependent and one independent of Neur. Their analysis suggests that one important role of Dl protein ubiquitination by Mib1 is their release from cis-inhibitory interactions with Notch, enabling them to trans-activate Notch on adjacent cells. | 28960177 |
| 2013-02-16 12:06:00 | the NHR2 domain is required for Neur function, and a point mutation in the NHR2 domain (Gly430) abolishes Neur ubiquitination activity and affects ligand internalization | 23045391 |
| 2012-02-11 10:58:00 | The ubiquitylation of Delta by both Neuralized and Mindbomb1 was detected, with the two enzymes using distinct docking sites and having different acceptor lysine preferences. | 22162135 |
| Type | IDs |
|---|---|
| Synonymous | 0328/12, 0971/15, 1293/09, 1315/05, BEST:LD21494, CG11988, Dmel\CG11988, Neur, l(3)j6B12, l(3)j9B8, l(3)j9B9, l(3)j9C8, l(3)neo37, neu |
| Gene |
UniProtKB-ID:
NEUR_DROME,
E1JIG1_DROME
UniprotKB:
P29503,
E1JIG1
UniParc:
UPI0000007532,
UPI000007EDF4,
UPI00000847D9,
UPI000000C156
EMBL:
BT003772,
X61617,
S62583,
S62597,
AY051987,
AE014297,
L12218
EnsemblGenome:
FBgn0002932
KO:
dme:Dmel_CG11988
|
| Nucleutide sequences |
EMBL-CDS:
AAA28403.1,
CAA43806.1,
AAB27147.1,
AAN13406.1,
AAO41451.1,
AAB27151.1,
AAN13407.1,
AAK93411.1,
AAF54326.2,
AAF54330.1,
ACZ94860.1
Gene_ORFName:
CG11988,
CG11988,
Dmel_CG11988
EnsemblGenome_TRS:
FBtr0082004,
FBtr0082001,
FBtr0300414,
FBtr0082003,
FBtr0082002,
FBtr0300414,
FBtr0082001
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0081480,
FBpp0081482,
FBpp0081479,
FBpp0289643,
FBpp0081481,
FBpp0289643,
FBpp0081479
RefSeq:
NP_731309.1,
NP_731310.1,
NP_001163563.1,
NP_476652.1,
NP_731311.1
|
| Others |
UniRef100:
UniRef100_E1JIG1,
UniRef100_P29503
UniRef90:
UniRef90_P29503
UniRef50:
UniRef50_P29503
UniGene:
Dm.1114
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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