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4103 MAGEA4

4103

MAGEA4

MAGE family member A4

protein-coding

Homo sapiens

基因描述

Type Description
Definition MAGE family member A4

研究结论

Date Results Publications
2021-02-02 13:26:00 MAGE-A4, NY-ESO-1 and mRNA expression rates and co-expression relationships in solid tumours. 32600281
2021-01-23 12:59:00 T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4. 32532817
2018-12-29 11:38:00 MAGEA4 was positively correlated with TWIST1, and its knockdown inhibited EMT in TE3 cells. 28653599
2018-11-03 11:06:00 Because of the significant correlation of MAGEA4 and indices of poor prognosis, the role of this CTA may be confirmed in Esophageal squamous cell carcinoma (ESCC) aggressiveness and metastasis. Therefore, MAGEA4 may be a promising therapeutic candidate for suppressing ESCC aggressiveness 30197348
2018-10-27 10:29:00 Study shows that whereas MAGEA4 expression by itself may be indicative of a poor prognosis in primary lung cancer, its prognostic value depends entirely on its subcellular localization and on the p53 status. The accumulation of nuclear MAGEA4 expression without p53 expression is significantly associated with poor survival, implying that MAGEA4 inhibits apoptosis and increases tumorigenesis. 29901069

名称对应

Type IDs
Synonymous CT1.4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B
Gene
UniProtKB-ID: MAGA4_HUMAN, A0A024RC12_HUMAN
UniprotKB: P43358, A0A024RC12
UniParc: UPI000013EA1F
EMBL: CH471169, D32077, D32075, U10687, BC017723, U10340, AF274855, U10688
Ensembl: ENSG00000147381
KO: hsa:4103
Nucleutide sequences
EMBL-CDS: AAA68871.1, AAA19007.1, AAH17723.1, AAA68872.1, BAA06843.1, BAA06841.1, EAW99411.1, EAW99412.1, EAW99413.1, EAW99410.1
Gene_ORFName: hCG_38709
Ensembl_TRS: ENST00000393920, ENST00000370340, ENST00000393921, ENST00000360243, ENST00000370335, ENST00000276344
Protein sequencees
Ensembl_PRO: ENSP00000359360, ENSP00000377498, ENSP00000276344, ENSP00000359365, ENSP00000377497, ENSP00000353379
RefSeq: NP_002353.3, NP_001011548.1, NP_001011550.1, NP_001373128.1, NP_001373131.1, NP_001373125.1, NP_001373132.1, NP_001373129.1, NP_001011549.1, NP_001373126.1, NP_001373127.1
Others
UniRef100: UniRef100_P43358
UniRef90: UniRef90_P43358
UniRef50: UniRef50_P43358
UniGene: Hs.37107
CCDS: CCDS14702.1

全选

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