例如:"NBL1", "4681", "drought"
收藏
4101 MAGEA2

4101

MAGEA2

MAGE family member A2

protein-coding

Homo sapiens

基因描述

Type Description
Definition MAGE family member A2

研究结论

Date Results Publications
2019-07-06 11:00:00 high MAGEA2 expression is an independent prognostic factor for glioma patient poor overall survival 30064232
2018-03-24 11:10:00 Data indicate that melanoma-associated antigen A2 (MAGEA2)is significantly overexpressed in triple-negative breast cancer (TNBC) tissues and is important for progression of TNBC and may serve as a novel molecular therapeutic target. 28415749
2018-03-03 10:43:00 suppression of MAGEA2 in lung cancer cells significantly reduced the growth/survival of cancer cells. High-MAGEA2 was identified as an independent prognostic factor in lung adenocarcinoma. Specific inhibition of MAGEA2 may be a promising therapeutic strategy for patients with lung cancer. 28498455
2017-01-28 10:18:00 Immunohistochemistry using D2-40 monoclonal antibody (MAGE2) and anti-MITF1 increased detection of lymphovascular invasion in primary cutaneous melanoma. 26675354
2016-04-23 10:55:00 We find that MAGE-A2 interacts with MDM2 via the N-terminal p53-binding pocket and the RING finger domain of MDM2 that is required for homo/hetero-dimerization and for E2 ligase interaction. 26001071

名称对应

Type IDs
Synonymous CT1.2, MAGE2, MAGEA2A
Gene
UniProtKB-ID: MAGA2_HUMAN, Q6P448_HUMAN, A0A024RC17_HUMAN
UniprotKB: P43356, Q6P448, A0A024RC17
UniParc: UPI0000227E55, UPI000012EB28
EMBL: BC112160, L18920, CH471169, BC112158, AK290443, BC108720, U82671, BC063681
Ensembl: ENSG00000268606, ENSG00000183305
KO: hsa:266740, hsa:4101
Nucleutide sequences
EMBL-CDS: BAF83132.1, AAI12159.1, AAI08721.1, EAW99429.1, AAI12161.1, AAA17729.1, AAH63681.1, EAW99431.1, EAW99430.1
Gene_ORFName: hCG_1739882
Ensembl_TRS: ENST00000370293, ENST00000611557, ENST00000611674, ENST00000598543, ENST00000623806, ENST00000595583, ENST00000620710, ENST00000331220, ENST00000623438
Protein sequencees
Ensembl_PRO: ENSP00000480738, ENSP00000484290, ENSP00000485391, ENSP00000480491, ENSP00000470872, ENSP00000485541, ENSP00000469919, ENSP00000359316, ENSP00000333487
RefSeq: NP_001269431.1, NP_001269434.1, NP_786885.1, NP_005352.1, NP_786884.1, NP_001269430.1, NP_001269433.1, NP_001373059.1
Others
UniRef100: UniRef100_Q6P448, UniRef100_P43356
UniRef90: UniRef90_P43356
UniRef50: UniRef50_P43356
UniGene: Hs.534597, Hs.713061
CCDS: CCDS76049.1, CCDS76046.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员