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40966 Ada2b

40966

Ada2b

transcriptional Adaptor 2b

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition transcriptional Adaptor 2b

研究结论

Date Results Publications
2019-11-02 12:21:00 demonstration that the fly ADA complex has histone acetylation activity on histones and nucleosome substrates; ChIP-Sequencing experiments identified Ada2b peaks that overlap with another SAGA subunit, Spt3, as well as Ada2b peaks that do not overlap with Spt3 suggesting that the ADA complex binds chromosomal sites independent of the larger SAGA complex 30715476
2013-06-29 12:27:00 different isoforms of dADA2b contribute to the functional variations of dSAGA multiprotein HAT complexes 23336284
2012-12-08 11:28:00 ADA2 C-terminal regions play an important role in the specific incorporation of ADA2 into SAGA- or ATAC-type complexes, which in turn determines H3- or H4-specific histone targeting. 22796493
2010-01-21 00:00:00 in vivo the two dADA2 proteins showed different localizations on polytene X chromosomes. These results, taken together, suggest that the two Drosophila ADA2 homologues are present in distinct GCN5-containing HAT complexes 12482983
2010-01-21 00:00:00 The ADA2b gene, functionally distinct homolog of ADA2a, is essential for the Drosophila development. 16135810

名称对应

Type IDs
Synonymous ADA2b, Ada2B, Ada2S, BcDNA:LD24527, CG9638, Dmel\CG9638, ada2b, dADA2b, dAda2B, dAda2S, dAda2b
Gene
UniProtKB-ID: TAD2B_DROME, A0A0B4KFU2_DROME
UniprotKB: Q8I8V0, A0A0B4KFU2
UniParc: UPI0000085B4F, UPI000007A2AE
EMBL: AE014297, AY058546, AY142213
EnsemblGenome: FBgn0037555
KO: dme:Dmel_CG9638
Nucleutide sequences
EMBL-CDS: AAN52141.1, AAF54199.1, AAZ52519.1, AAL13775.1, AGB95749.1
Gene_ORFName: CG9638, Dmel_CG9638, CG9638
EnsemblGenome_TRS: FBtr0081807, FBtr0100368, FBtr0334315, FBtr0334315, FBtr0081807
Protein sequencees
EnsemblGenome_PRO: FBpp0306430, FBpp0081303, FBpp0099776, FBpp0306430, FBpp0081303
RefSeq: NP_649773.1, NP_001262367.1, NP_001027151.1
Others
UniRef100: UniRef100_Q8I8V0, UniRef100_A0A0B4KFU2
UniRef90: UniRef90_Q8I8V0, UniRef90_A0A0B4KFU2
UniRef50: UniRef50_Q8I8V0, UniRef50_A0A0B4KFU2
UniGene: Dm.20776

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