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40913 Nlg1

40913

Nlg1

Neuroligin 1

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Neuroligin 1

研究结论

Date Results Publications
2019-07-13 11:41:00 The authors find that axonal branch growth is regulated by dynamic, focal localisations of Neurexin and Neuroligin. These adhesion complexes provide stability for filopodia by a 'stick-and-grow' based mechanism wholly independent of synaptic activity. 29504935
2019-07-06 10:38:00 The disruption of DNlg1, DNlg2, or their presynaptic partner neurexin (DNrx) led to a dramatic decrease in the amount of F-actin. Further study showed that DNlg1, but not DNlg2 or DNlg3, directly interacts with the WRC via its C-terminal interacting receptor sequence. 29537369
2018-01-27 11:13:00 dnlg1 mutants have reduced levels of Wit. Dnlg1 is required for proper localization and stability of Wit. 27838296
2017-11-18 11:49:00 Genetic interaction experiments demonstrate Syx4, Syt4, and Nlg1 regulate synaptic growth and plasticity through both shared and parallel signaling pathways. 27223326
2016-05-28 11:12:00 presynaptic spinophilin fine-tunes neurexin/neuroligin signalling to control active zone number and functionality 26471740

名称对应

Type IDs
Synonymous CG12148, CG14596, CG31146, DNlg1, Dmel\CG31146, anon-WO0118547.256, dnlg1, nlg1
Gene
UniProtKB-ID: Q9VIC7_DROME
UniprotKB: Q9VIC7
UniParc: UPI00000074FC
EMBL: BT024213, AE014297
EnsemblGenome: FBgn0051146
KO: dme:Dmel_CG31146
Nucleutide sequences
EMBL-CDS: AAF53998.3, ABC86275.1, AFH06285.1
Gene_ORFName: Dmel_CG31146, CG31146
EnsemblGenome_TRS: FBtr0305969, FBtr0081541
Protein sequencees
EnsemblGenome_PRO: FBpp0297111, FBpp0081065
RefSeq: NP_731172.2, NP_001246966.1
Others
UniRef100: UniRef100_Q9VIC7
UniRef90: UniRef90_Q9VIC7
UniRef50: UniRef50_Q9VIC7
UniGene: Dm.17107

全选

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研究热度

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