| Type | Description |
|---|---|
| Definition | Spindle assembly abnormal 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:59:00 | The Singularity of the Drosophila Male Germ Cell Centriole: The Asymmetric Distribution of Sas4 and Sas6. | 31947732 |
| 2020-02-22 13:06:00 | Here, the authors show that PLK4 phosphorylates its centriole substrate STIL on a conserved site, S428, to promote STIL binding to CPAP. This phospho-dependent binding interaction is conserved in Drosophila and facilitates the stable incorporation of both STIL and CPAP into the centriole. | 31115335 |
| 2019-12-07 10:38:00 | These observations identify Plk1/Polo kinase regulation of Sas-4 as essential for efficient pericentriolar material expansion. | 30590037 |
| 2019-09-07 10:49:00 | By halfway through pupal life, the centriole number decreases and structural defects, ranging from being incomplete or lacking B-tubules, are detected. Asl, Ana1 and Sas-4 are still present, suggesting that the centriole integrity does not depend on these proteins. | 29361550 |
| 2017-06-24 12:27:00 | Cdk1 phosphorylates the conserved centriole protein Sas-4 during mitosis. This creates a Polo-docking site that helps recruit Polo to daughter centrioles. | 27326932 |
| Type | IDs |
|---|---|
| Synonymous | CG10061, CPAP, D-Sas4, D-sas4, DSAS-4, DSas-4, DSas4, Dmel\CG10061, Dsas-4, Dsas4, SAS-4, SAS4, Sas4, d-SAS-4, dsas-4, l(3)S2214, l(3)s2214, sas-4, sas4 |
| Gene |
UniProtKB-ID:
Q9VI72_DROME
UniprotKB:
Q9VI72
UniParc:
UPI000034DF84
EMBL:
AE014297
EnsemblGenome:
FBgn0011020
KO:
dme:Dmel_CG10061
|
| Nucleutide sequences |
EMBL-CDS:
AAF54053.2
Gene_ORFName:
Dmel_CG10061,
CG10061
EnsemblGenome_TRS:
FBtr0081569
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0081088
RefSeq:
NP_649701.2
|
| Others |
UniRef100:
UniRef100_Q9VI72
UniRef90:
UniRef90_Q9VI72
UniRef50:
UniRef50_Q9VI72
UniGene:
Dm.17121
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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