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4085 MAD2L1

4085

MAD2L1

mitotic arrest deficient 2 like 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition mitotic arrest deficient 2 like 1

研究结论

Date Results Publications
2020-12-12 13:24:00 Mitotic slippage is determined by p31(comet) and the weakening of the spindle-assembly checkpoint. 32029899
2020-11-21 13:27:00 Analysis of TET2 and EZH2 gene functions in chromosome instability in acute myeloid leukemia. 32066746
2020-06-06 13:18:00 Downregulation of Mad2 and BubR1 increase the malignant behavior and nocodazole resistance of SiHa cells via causing spindle assembly checkpoint defect. 31523901
2020-06-06 12:45:00 human shugoshin 2, an essential protector of meiotic cohesin with unknown functions in the soma, is turned into a separase inhibitor upon association with spindle assembly checkpoint-activated MAD2 32322060
2020-02-29 11:01:00 the present study revealed that PTEN knockdown resulted in MAD2 degradation via the ubiquitinproteasomal pathway, while restoration of MAD2 expression partially ameliorated the mitotic defects induced by PTEN loss. 31545428

名称对应

Type IDs
Synonymous HSMAD2, MAD2
Gene
UniProtKB-ID: MD2L1_HUMAN
UniprotKB: Q13257
UniParc: UPI000007408B, UPI0000000A29
EMBL: BC070283, BC000356, U65410, AF202269, U31278, AB056160, AC097173, AK313827, AF202270, AF202271, BC005945, AF202272, AK223433, AF202273, CH471056, AJ000186, AF394735, AK298228
Ensembl: ENSG00000164109
KO: hsa:4085
Nucleutide sequences
EMBL-CDS: AAY40945.1, AAC50781.1, AAC52060.1, AAH05945.1, AAN74648.1, EAX05271.1, AAH00356.1, BAD97153.1, BAG36562.1, EAX05273.1, AAK38174.1, CAA03943.1, AAH70283.1, BAB63410.1, BAG60497.1
Ensembl_TRS: ENST00000296509, ENST00000333047
Protein sequencees
Ensembl_PRO: ENSP00000332295, ENSP00000296509
RefSeq: NP_002349.1
Others
UniRef100: UniRef100_Q13257
UniRef90: UniRef90_Q13257
UniRef50: UniRef50_Q13257
UniGene: Hs.591697
CCDS: CCDS3715.1

全选

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