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40847 Tailor

40847

Tailor

tailor

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition tailor

研究结论

Date Results Publications
2019-08-31 13:09:00 our work reveals useful insights to explain why Drosophila Tailor can preferentially select RNA substrates ending in 3'G and provides important values for further understanding the biological significances of biogenesis pathway of mirtron in flies. 30407553
2019-08-24 11:59:00 Analysis of crystal structures reveal specific amino acid residues of Tailor that are involved in donor and acceptor substrate recognition, and complementary biochemical assays confirm the critical role of an active site arginine in conferring selectivity toward 3'-guanosine terminated RNAs. 30462292
2017-09-09 12:53:00 The mutants of Tailor and Dis3L2 are viable and lack overt morphological defects. Instead, these mutants exhibit defects in female and male fertility, implying specific requirements in the germline. 27974621
2015-10-17 11:22:00 detect preferential activity of Tailor on 3'-G canonical pre-miRNAs, and specific depletion of such loci from the pool of conserved miRNAs 26145174
2015-10-17 11:22:00 Tailor is an uridylyltransferase that is required for the majority of 3' end modifications of microRNAs and predominantly targets precursor hairpins 26145176

名称对应

Type IDs
Synonymous CG1091, Dmel\CG1091, anon-WO0118547.222
Gene
UniProtKB-ID: TUTT_DROME, A0A0B4KGN4_DROME, Q86BP3_DROME
UniprotKB: Q9VI58, A0A0B4KGN4, Q86BP3
UniParc: UPI000000750A, UPI0000007509, UPI0002945110
EMBL: AE014297, AY071118
EnsemblGenome: FBgn0037470
KO: dme:Dmel_CG1091
Nucleutide sequences
EMBL-CDS: AAF54068.3, AAL48740.1, AGB95710.1, AAN13359.1
Gene_ORFName: CG1091, CG1091, Dmel_CG1091, CG1091, Dmel_CG1091
EnsemblGenome_TRS: FBtr0081640, FBtr0333326, FBtr0081641
Protein sequencees
EnsemblGenome_PRO: FBpp0081154, FBpp0305518, FBpp0081155
RefSeq: NP_731129.1, NP_649693.3, NP_001262327.1
Others
UniRef100: UniRef100_A0A0B4KGN4, UniRef100_Q9VI58
UniRef90: UniRef90_Q9VI58
UniRef50: UniRef50_Q9VI58
UniGene: Dm.6108

全选

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研究热度

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