| Type | Description |
|---|---|
| Definition | MAX dimerization protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:22:00 | MXD1 regulates the H9N2 and H1N1 influenza A virus-induced chemokine expression and their replications in human macrophage. | 32794336 |
| 2020-02-29 12:22:00 | Compared with noncancerous breast tissues, miRNA-382-5p expression was upregulated but MXD1 mRNA expression was downregulated in breast cancer tissues. The dysregulation of miRNA-382-5p-MXD1 axis may be involved in the development and aggressive progression of breast cancer. miRNA-382-5p may target MXD1, leading to cell invasion and proliferation in breast cancer cells in vitro. | 31635836 |
| 2019-06-08 10:42:00 | these data show that MXD1 functions as a negative regulator of BCR-ABL1 expression and subsequently inhibits proliferation and sensitizes chronic myeloid leukemia cells to imatinib treatment | 30419548 |
| 2018-02-17 11:18:00 | Results suggest a role for MAX dimerization protein 1 (MXD1) in the control of ribosome biogenesis. | 27588501 |
| 2017-10-07 11:44:00 | Study revealed that HIF-1alpha-induced Mxd1 contributes to cisplatin-resistance in hypoxic osteosarcoma cells by directly repressing PTEN, which leads to the activation of PI3K/AKT antiapoptotic and survival pathway. | 28543796 |
| Type | IDs |
|---|---|
| Synonymous | BHLHC58, MAD, MAD1 |
| Gene |
UniProtKB-ID:
MAD1_HUMAN,
B7ZLI7_HUMAN
UniprotKB:
Q05195,
B7ZLI7
UniParc:
UPI0000035C7D,
UPI000189A7A5,
UPI000189A7A4
EMBL:
CH471053,
L06895,
BC069433,
AK312734,
BC098396,
BC113531,
BC143831,
BC069377,
CR536495,
BC117260,
AC019206,
BC143832,
CR541692
Ensembl:
ENSG00000059728
KO:
hsa:4084
|
| Nucleutide sequences |
EMBL-CDS:
AAH69433.1,
AAI17261.1,
AAI43832.1,
AAH69377.1,
CAG38734.1,
AAH98396.1,
AAY14867.1,
AAI13532.1,
EAW99839.1,
BAG35605.1,
AAA36194.1,
CAG46493.1,
AAI43833.1
Ensembl_TRS:
ENST00000540449,
ENST00000264444
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000443935,
ENSP00000264444
RefSeq:
NP_001189442.1,
NP_002348.1,
NP_001189443.1
|
| Others |
UniRef100:
UniRef100_Q05195,
UniRef100_B7ZLI7
UniRef90:
UniRef90_Q05195
UniRef50:
UniRef50_Q05195
UniGene:
Hs.468908
CCDS:
CCDS56123.1,
CCDS1896.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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