| Type | Description |
|---|---|
| Definition | Sex combs reduced |
| Date | Results | Publications |
|---|---|---|
| 2018-06-30 10:18:00 | Data show that the Distalless and Engrailed homeodomain transcription factors act through sequences in this enhancer to establish elevated Sex combs reduced (Scr) expression in spatially defined domains. | 29634724 |
| 2016-03-19 10:09:00 | Results from NMR spectroscopy show that spontaneous deamidation of Scr protein at residue Asn 321 reduces its affinity for target DNA. | 26435141 |
| 2015-07-04 14:39:00 | To test if Hox proteins directly use shape readout, study characterized Exd-Scr co-crystal structures. When minor groove-inserting residues of Scr were mutated to alanines, thus impairing its ability to use shape readout, the mutant proteins no longer preferred sequences containing these minor groove width minima. | 25843630 |
| 2014-03-22 11:40:00 | male-like pattern of SCR expression is independent of dsx function, and dsx F must be responsible for bringing about dimorphism in SCR expression, whereas dsx M function is required with Scr for the morphogenesis of sex comb. | 23938378 |
| 2013-12-14 10:47:00 | Study shows that the LASCY, DYTQL, NANGE motifs, and the C-terminal domain of SCR mediate suppression of induction of ectopic proboscis identity, which would explain why co-expression of PB and SCR is unable to induce ectopic proboscises. | 24121940 |
| Type | IDs |
|---|---|
| Synonymous | BG:DS07876.2, CG1030, DmScr, Dmel\CG1030, Msc, SCR, l(3)84Af, scr |
| Gene |
UniProtKB-ID:
SCR_DROME,
A4V2I1_DROME
UniprotKB:
P09077,
A4V2I1
UniParc:
UPI000007786B
EMBL:
X14475,
AE001572,
AE014297,
X77075,
U10506,
X77076,
X05228
EnsemblGenome:
FBgn0003339
KO:
dme:Dmel_CG1030
|
| Nucleutide sequences |
EMBL-CDS:
CAA54348.1,
CAA32637.1,
AAD19795.1,
AAF54082.1,
CAA28857.1,
AAA19240.1,
AAS65103.1
Gene_ORFName:
CG1030,
Dmel_CG1030,
CG1030
EnsemblGenome_TRS:
FBtr0081657,
FBtr0081658,
FBtr0081658,
FBtr0081657
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0089393,
FBpp0081163,
FBpp0081163,
FBpp0089393
RefSeq:
NP_001356915.1,
NP_001356897.1,
NP_001368995.1,
NP_524248.2,
NP_996165.1
|
| Others |
UniRef100:
UniRef100_P09077
UniRef90:
UniRef90_P09077
UniRef50:
UniRef50_P09077
UniGene:
Dm.2481
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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