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407639 gh1

407639

gh1

growth hormone 1

protein-coding

Danio rerio

基因描述

Type Description
Definition growth hormone 1

研究结论

Date Results Publications
2018-01-06 11:17:00 Reproductive tests showed that double transgenic males did not differ from non-transgenics. It is possible that GHR excess in the muscle tissues of double transgenics may have contributed to lower circulating GH levels and thus reduced the negative effects of this hormone with respect to reproduction. 27743222
2016-09-17 11:29:00 that concomitant overexpression of GH and GHR resulted in a strong decrease of the somatotrophic axis intracellular signaling by diminishing its principal transcription factor signal transducer and activator of transcription 5.1. 26574627
2016-04-09 11:35:00 Effects of somatotrophic axis (GH/GHR) double transgenesis on structural and molecular aspects of the zebrafish immune system 26052013
2013-05-11 12:19:00 The zebrafish gh1 mutant, vizzini, exhibits decreased somatic growth, increased adipose tissue accumulation, and disrupted adipose plasticity after nutrient deprivation. 23456361
2013-01-05 11:51:00 tbx5 knockdown causes a pseudo GH deficiency in zebrafish during early embryonic stages, and supplementation of exogenous GH can partially restore dysmorphogenesis, apoptosis, cell growth inhibition, and abnormal cardiomyogenesis 22776023

名称对应

Type IDs
Synonymous ghl
Gene
UniProtKB-ID: Q1JQ34_DANRE
UniprotKB: Q1JQ34
UniParc: UPI00001547F8
EMBL: BC116501, BX005440
Ensembl: ENSDARG00000038185
KO: dre:407639
Nucleutide sequences
EMBL-CDS: AAI16502.1
Ensembl_TRS: ENSDART00000055675
Protein sequencees
Ensembl_PRO: ENSDARP00000055674
RefSeq: NP_001018328.2
Others
UniRef100: UniRef100_Q1JQ34
UniRef90: UniRef90_Q1JQ34
UniRef50: UniRef50_P09538
UniGene: Dr.30452

全选

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研究热度

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